Restoration of TP53 strategy via specific nanoparticles for ovarian cancer therapy
Abstract The p53 tumor suppressor gene, a master regulator of diverse cellular pathways, is frequently altered in various cancers. Loss of function in tumor suppressor genes is commonly associated with the onset/progression of cancer and treatment resistance. Currently, approaches for restoration of...
Saved in:
| Main Authors: | Menglei Zhang, Yuanyuan Gu, Fang Shen, Yingxin Gong, Zheng Gu, Keqin Hua, Guannan Zhou, Jingxin Ding |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Journal of Ovarian Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13048-025-01672-9 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
TP53 and KRAS co-mutations are associated with worse outcomes in mucinous ovarian carcinomas
by: Yingao Zhang, et al.
Published: (2025-08-01) -
Functional validation of somatic variability in TP53 and KRAS for prediction of platinum sensitivity and prognosis in epithelial ovarian carcinoma patients
by: Al Obeed Allah Mohammad, et al.
Published: (2025-12-01) -
In-frame germline TP53 variant impairs p53 oligomerization and predisposes to cancer
by: Lucie Vanikova, et al.
Published: (2025-08-01) -
Impact of TP53 mutations on the efficacy of CAR-T cell therapy in cancer
by: Regina Mirgayazova, et al.
Published: (2024-12-01) -
CircTP53/USP10/p53 signaling Axis as a Novel Regulator of Progression and Prognosis of Head and Neck Squamous Cell Carcinoma
by: Yin Wang, et al.
Published: (2025-08-01)