Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy
Malignant phyllodes tumors of the breast occur infrequently and are difficult to treat with chemotherapy. Here, we present an effective chemotherapy strategy for recurrent malignant breast phyllodes tumors. A 48-year-old woman was diagnosed with a malignant phyllodes tumor in her right breast and un...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/2759650 |
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| _version_ | 1832559514445938688 |
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| author | Shinya Yamamoto Shigeru Yamagishi Toshiro Kohno Ryosuke Tajiri Toshikazu Gondo Noboru Yoshimoto Nobuko Kusano |
| author_facet | Shinya Yamamoto Shigeru Yamagishi Toshiro Kohno Ryosuke Tajiri Toshikazu Gondo Noboru Yoshimoto Nobuko Kusano |
| author_sort | Shinya Yamamoto |
| collection | DOAJ |
| description | Malignant phyllodes tumors of the breast occur infrequently and are difficult to treat with chemotherapy. Here, we present an effective chemotherapy strategy for recurrent malignant breast phyllodes tumors. A 48-year-old woman was diagnosed with a malignant phyllodes tumor in her right breast and underwent total right mastectomy. One year later, the tumor recurred in the right (a 2.2 cm mass) and left (a 10 cm mass) lungs; pleural effusion was also observed in the left lung. Eight courses of doxorubicin-ifosfamide (AI) therapy were administered. After treatment, the right lung mass and pleural effusion regressed completely and the left lung mass regressed to 2 cm. In conclusion, AI therapy is useful for treating recurrent malignant breast phyllodes tumors. |
| format | Article |
| id | doaj-art-cfda423172d24419bae278bacfba1240 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-cfda423172d24419bae278bacfba12402025-02-03T01:29:59ZengWileyCase Reports in Oncological Medicine2090-67062090-67142019-01-01201910.1155/2019/27596502759650Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide TherapyShinya Yamamoto0Shigeru Yamagishi1Toshiro Kohno2Ryosuke Tajiri3Toshikazu Gondo4Noboru Yoshimoto5Nobuko Kusano6Department of Breast Surgery, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa City, Kanagawa 251-8550, JapanDepartment of Breast Surgery, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa City, Kanagawa 251-8550, JapanShonan Fujisawa Clinic, 1-15 Hanazawa-cho, Kugenuma, Fujisawa City, Kanagawa 251-0023, JapanDepartment of Diagnostic Pathology, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa City, Kanagawa 251-8550, JapanDepartment of Diagnostic Pathology, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa City, Kanagawa 251-8550, JapanDepartment of Thoracic Surgery, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa City, Kanagawa 251-8550, JapanAmbulatory Treatment Center, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa City, Kanagawa 251-8550, JapanMalignant phyllodes tumors of the breast occur infrequently and are difficult to treat with chemotherapy. Here, we present an effective chemotherapy strategy for recurrent malignant breast phyllodes tumors. A 48-year-old woman was diagnosed with a malignant phyllodes tumor in her right breast and underwent total right mastectomy. One year later, the tumor recurred in the right (a 2.2 cm mass) and left (a 10 cm mass) lungs; pleural effusion was also observed in the left lung. Eight courses of doxorubicin-ifosfamide (AI) therapy were administered. After treatment, the right lung mass and pleural effusion regressed completely and the left lung mass regressed to 2 cm. In conclusion, AI therapy is useful for treating recurrent malignant breast phyllodes tumors.http://dx.doi.org/10.1155/2019/2759650 |
| spellingShingle | Shinya Yamamoto Shigeru Yamagishi Toshiro Kohno Ryosuke Tajiri Toshikazu Gondo Noboru Yoshimoto Nobuko Kusano Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy Case Reports in Oncological Medicine |
| title | Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy |
| title_full | Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy |
| title_fullStr | Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy |
| title_full_unstemmed | Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy |
| title_short | Effective Treatment of a Malignant Breast Phyllodes Tumor with Doxorubicin-Ifosfamide Therapy |
| title_sort | effective treatment of a malignant breast phyllodes tumor with doxorubicin ifosfamide therapy |
| url | http://dx.doi.org/10.1155/2019/2759650 |
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