Comprehensive Overview of Methods of Pregnancy Termination in Macaques and Marmosets
Limited information is available concerning the termination of pregnancy in non-human primates. Thus, a comprehensive review of this topic will be beneficial for veterinary staff in laboratories, zoos, and wildlife rehabilitation centers. The most relevant studies concerning the termination of viabl...
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MDPI AG
2024-10-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/11/11/527 |
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| author | Tommaso Virgilio Remco A. Nederlof Mallory G. Brown Jaco Bakker |
| author_facet | Tommaso Virgilio Remco A. Nederlof Mallory G. Brown Jaco Bakker |
| author_sort | Tommaso Virgilio |
| collection | DOAJ |
| description | Limited information is available concerning the termination of pregnancy in non-human primates. Thus, a comprehensive review of this topic will be beneficial for veterinary staff in laboratories, zoos, and wildlife rehabilitation centers. The most relevant studies concerning the termination of viable and non-viable pregnancy in non-human primates were analyzed, and dosages, administration routes, adverse effects, and the efficacy of the drugs used are reported. The literature revealed that termination of pregnancy is most commonly performed in marmosets and macaques. The combination of mifepristone and misoprostol was reported to be effective and fast-acting in terminating first-trimester pregnancy in macaques, while cloprostenol was identified as the best agent for use in marmosets. This review also provides insights about the limitations of previously described methods of pregnancy termination and discusses potential alternatives and areas for future investigation. |
| format | Article |
| id | doaj-art-cfd9b52a73654b809164dab49db9d144 |
| institution | OA Journals |
| issn | 2306-7381 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj-art-cfd9b52a73654b809164dab49db9d1442025-08-20T01:53:56ZengMDPI AGVeterinary Sciences2306-73812024-10-01111152710.3390/vetsci11110527Comprehensive Overview of Methods of Pregnancy Termination in Macaques and MarmosetsTommaso Virgilio0Remco A. Nederlof1Mallory G. Brown2Jaco Bakker3Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, SwitzerlandIndependent Researcher, 2861 XZ Bergambacht, The NetherlandsIndependent Researcher, Baltimore, MD 21224, USAAnimal Science Department, Biomedical Primate Research Centre, 2288 GJ Rijswijk, The NetherlandsLimited information is available concerning the termination of pregnancy in non-human primates. Thus, a comprehensive review of this topic will be beneficial for veterinary staff in laboratories, zoos, and wildlife rehabilitation centers. The most relevant studies concerning the termination of viable and non-viable pregnancy in non-human primates were analyzed, and dosages, administration routes, adverse effects, and the efficacy of the drugs used are reported. The literature revealed that termination of pregnancy is most commonly performed in marmosets and macaques. The combination of mifepristone and misoprostol was reported to be effective and fast-acting in terminating first-trimester pregnancy in macaques, while cloprostenol was identified as the best agent for use in marmosets. This review also provides insights about the limitations of previously described methods of pregnancy termination and discusses potential alternatives and areas for future investigation.https://www.mdpi.com/2306-7381/11/11/527marmosetsmacaquesabortionfetal demisemisoprostolprimates |
| spellingShingle | Tommaso Virgilio Remco A. Nederlof Mallory G. Brown Jaco Bakker Comprehensive Overview of Methods of Pregnancy Termination in Macaques and Marmosets Veterinary Sciences marmosets macaques abortion fetal demise misoprostol primates |
| title | Comprehensive Overview of Methods of Pregnancy Termination in Macaques and Marmosets |
| title_full | Comprehensive Overview of Methods of Pregnancy Termination in Macaques and Marmosets |
| title_fullStr | Comprehensive Overview of Methods of Pregnancy Termination in Macaques and Marmosets |
| title_full_unstemmed | Comprehensive Overview of Methods of Pregnancy Termination in Macaques and Marmosets |
| title_short | Comprehensive Overview of Methods of Pregnancy Termination in Macaques and Marmosets |
| title_sort | comprehensive overview of methods of pregnancy termination in macaques and marmosets |
| topic | marmosets macaques abortion fetal demise misoprostol primates |
| url | https://www.mdpi.com/2306-7381/11/11/527 |
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