Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastography
Background & objective: Advancements in breast tumor screening and diagnosis are crucial for improving treatment outcomes and reducing mortality rates. This study evaluated the diagnostic accuracy of integrating quantitative shear wave elastography with B-mode ultrasonography to differentiate be...
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Kurdistan Higher Council Of Medical Specialties
2025-03-01
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| Series: | Advanced Medical Journal |
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| Online Access: | https://amj.khcms.edu.krd/index.php/main/article/view/584 |
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| author | Shadan Jasim Mohammed Saeed Nadhim Younis Agha |
| author_facet | Shadan Jasim Mohammed Saeed Nadhim Younis Agha |
| author_sort | Shadan Jasim Mohammed |
| collection | DOAJ |
| description | Background & objective: Advancements in breast tumor screening and diagnosis are crucial for improving treatment outcomes and reducing mortality rates. This study evaluated the diagnostic accuracy of integrating quantitative shear wave elastography with B-mode ultrasonography to differentiate benign from malignant breast lesions, keeping histopathology as reference standard.
Methods: This cross-sectional observational study implemented in Breast center in Erbil, Kurdistan, from May to September 2022. The women with breast mass were examined clinically by breast surgeon at the center and then referred to Radiology department for imaging. Both B-mode Ultrasound and Shear Wave Elastography were performed on 45 US-detected breast masses prior to any biopsy procedures. For each detected lesion, two key parameters were assessed: The Breast Imaging Reporting and Data System category based on B-mode ultrasound images and the mean elasticity values obtained from Shear Wave Sono elastography images. This dual approach aimed to provide a comprehensive evaluation of each lesion. Following the imaging, histopathological diagnoses were obtained for all lesions, taken as the gold standard.
Results: Histopathological examination, carried out by a specialized radiologist using core biopsy and Fine Needle Aspiration Cytology and analyzed by a pathologist with a consistent assessment protocol, revealed 55.6%benign and 44.4% malignant. B-mode ultrasound using the BI-RADS system, categorized 71.1% as BI-RADS 4, 15.6% as BI-RADS 5, and 13.3% as BI-RADS 3. Shear Wave Sono elastography proved critical, revealing significantly higher mean elasticity malignant cases (p<0.001. A strong correlation was found between increased elasticity and malignancy, as well as between elasticity and BI-RADS categorization (p=0.004). Malignant tumors had a direct link to elasticity (p=0.02). The optimal cutoff mean shear wave elasticity was 80 kPa with 90%sensitivity, 80% specificity and 84.4%accuracy.
Conclusions: Quantitative shear wave Sono elastography, combined with B-mode ultrasonography effectively categorize breast lesions, correlating strongly with histopathological findings. It emerges as a vital, non-invasive diagnostic tool, enhancing the accuracy of breast lesions characterization. |
| format | Article |
| id | doaj-art-cfd8eed7ec7e44efb999390baa6a9471 |
| institution | OA Journals |
| issn | 2958-8979 2957-3580 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Kurdistan Higher Council Of Medical Specialties |
| record_format | Article |
| series | Advanced Medical Journal |
| spelling | doaj-art-cfd8eed7ec7e44efb999390baa6a94712025-08-20T02:19:40ZengKurdistan Higher Council Of Medical SpecialtiesAdvanced Medical Journal2958-89792957-35802025-03-011011927https://doi.org/10.56056/amj.2025.313585Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastographyShadan Jasim Mohammed0Saeed Nadhim Younis Agha1M.B.Ch.B., Rizgary Teaching Hospital, Radiology DepartmentM.B.Ch.B, DMRD, Ph.D., Professor of Radiology, Kurdistan Board of Medical SpecialtiesBackground & objective: Advancements in breast tumor screening and diagnosis are crucial for improving treatment outcomes and reducing mortality rates. This study evaluated the diagnostic accuracy of integrating quantitative shear wave elastography with B-mode ultrasonography to differentiate benign from malignant breast lesions, keeping histopathology as reference standard. Methods: This cross-sectional observational study implemented in Breast center in Erbil, Kurdistan, from May to September 2022. The women with breast mass were examined clinically by breast surgeon at the center and then referred to Radiology department for imaging. Both B-mode Ultrasound and Shear Wave Elastography were performed on 45 US-detected breast masses prior to any biopsy procedures. For each detected lesion, two key parameters were assessed: The Breast Imaging Reporting and Data System category based on B-mode ultrasound images and the mean elasticity values obtained from Shear Wave Sono elastography images. This dual approach aimed to provide a comprehensive evaluation of each lesion. Following the imaging, histopathological diagnoses were obtained for all lesions, taken as the gold standard. Results: Histopathological examination, carried out by a specialized radiologist using core biopsy and Fine Needle Aspiration Cytology and analyzed by a pathologist with a consistent assessment protocol, revealed 55.6%benign and 44.4% malignant. B-mode ultrasound using the BI-RADS system, categorized 71.1% as BI-RADS 4, 15.6% as BI-RADS 5, and 13.3% as BI-RADS 3. Shear Wave Sono elastography proved critical, revealing significantly higher mean elasticity malignant cases (p<0.001. A strong correlation was found between increased elasticity and malignancy, as well as between elasticity and BI-RADS categorization (p=0.004). Malignant tumors had a direct link to elasticity (p=0.02). The optimal cutoff mean shear wave elasticity was 80 kPa with 90%sensitivity, 80% specificity and 84.4%accuracy. Conclusions: Quantitative shear wave Sono elastography, combined with B-mode ultrasonography effectively categorize breast lesions, correlating strongly with histopathological findings. It emerges as a vital, non-invasive diagnostic tool, enhancing the accuracy of breast lesions characterization.https://amj.khcms.edu.krd/index.php/main/article/view/584bi-radsbreast massshear wave elastographyultrasonography |
| spellingShingle | Shadan Jasim Mohammed Saeed Nadhim Younis Agha Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastography Advanced Medical Journal bi-rads breast mass shear wave elastography ultrasonography |
| title | Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastography |
| title_full | Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastography |
| title_fullStr | Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastography |
| title_full_unstemmed | Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastography |
| title_short | Imaging Characterization of Local Breast Lesions Using Shear Wave Sono elastography |
| title_sort | imaging characterization of local breast lesions using shear wave sono elastography |
| topic | bi-rads breast mass shear wave elastography ultrasonography |
| url | https://amj.khcms.edu.krd/index.php/main/article/view/584 |
| work_keys_str_mv | AT shadanjasimmohammed imagingcharacterizationoflocalbreastlesionsusingshearwavesonoelastography AT saeednadhimyounisagha imagingcharacterizationoflocalbreastlesionsusingshearwavesonoelastography |