A review of COVID-19 vaccination and the reported cardiac manifestations
In Singapore, 9.03 million doses of the mRNA COVID-19 vaccines by Pfizer-BioNTech and Moderna have been administered, and 4.46 million people are fully vaccinated. An additional 87,000 people have been vaccinated with vaccines in World Health Organization’s Emergency Use Listing. The aim of this rev...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer – Medknow Publications
2023-09-01
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| Series: | Singapore Medical Journal |
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| Online Access: | https://journals.lww.com/10.11622/smedj.2021210 |
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| _version_ | 1823861429664481280 |
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| author | Jamie Sin Ying Ho Ching-Hui Sia Jinghao Nicholas Ngiam Poay Huan Loh Nicholas Wen Sheng Chew William Kok-Fai Kong Kian-Keong Poh |
| author_facet | Jamie Sin Ying Ho Ching-Hui Sia Jinghao Nicholas Ngiam Poay Huan Loh Nicholas Wen Sheng Chew William Kok-Fai Kong Kian-Keong Poh |
| author_sort | Jamie Sin Ying Ho |
| collection | DOAJ |
| description | In Singapore, 9.03 million doses of the mRNA COVID-19 vaccines by Pfizer-BioNTech and Moderna have been administered, and 4.46 million people are fully vaccinated. An additional 87,000 people have been vaccinated with vaccines in World Health Organization’s Emergency Use Listing. The aim of this review is to explore the reported cardiac adverse events associated with different types of COVID-19 vaccines. A total of 42 studies that reported cardiac side effects after COVID-19 vaccination were included in this study. Reported COVID-19 vaccine-associated cardiac adverse events were mainly myocarditis and pericarditis, most commonly seen in adolescent and young adult male individuals after mRNA vaccination. Reports of other events such as acute myocardial infarction, arrhythmia and stress cardiomyopathy were rare. Outcomes of post-vaccine myocarditis and pericarditis were good. Given the good vaccine efficacy and the high number of cases of infection, hospitalisation and death that could potentially be prevented, COVID-19 vaccine remains of overall benefit, based on the current available data. |
| format | Article |
| id | doaj-art-cfd797ee3a164b58bff6489227ddd9e2 |
| institution | Kabale University |
| issn | 0037-5675 2737-5935 |
| language | English |
| publishDate | 2023-09-01 |
| publisher | Wolters Kluwer – Medknow Publications |
| record_format | Article |
| series | Singapore Medical Journal |
| spelling | doaj-art-cfd797ee3a164b58bff6489227ddd9e22025-02-09T14:00:00ZengWolters Kluwer – Medknow PublicationsSingapore Medical Journal0037-56752737-59352023-09-0164954354910.11622/smedj.2021210A review of COVID-19 vaccination and the reported cardiac manifestationsJamie Sin Ying HoChing-Hui SiaJinghao Nicholas NgiamPoay Huan LohNicholas Wen Sheng ChewWilliam Kok-Fai KongKian-Keong PohIn Singapore, 9.03 million doses of the mRNA COVID-19 vaccines by Pfizer-BioNTech and Moderna have been administered, and 4.46 million people are fully vaccinated. An additional 87,000 people have been vaccinated with vaccines in World Health Organization’s Emergency Use Listing. The aim of this review is to explore the reported cardiac adverse events associated with different types of COVID-19 vaccines. A total of 42 studies that reported cardiac side effects after COVID-19 vaccination were included in this study. Reported COVID-19 vaccine-associated cardiac adverse events were mainly myocarditis and pericarditis, most commonly seen in adolescent and young adult male individuals after mRNA vaccination. Reports of other events such as acute myocardial infarction, arrhythmia and stress cardiomyopathy were rare. Outcomes of post-vaccine myocarditis and pericarditis were good. Given the good vaccine efficacy and the high number of cases of infection, hospitalisation and death that could potentially be prevented, COVID-19 vaccine remains of overall benefit, based on the current available data.https://journals.lww.com/10.11622/smedj.2021210cardiac side effectscovid-19myocarditispericarditisvaccination |
| spellingShingle | Jamie Sin Ying Ho Ching-Hui Sia Jinghao Nicholas Ngiam Poay Huan Loh Nicholas Wen Sheng Chew William Kok-Fai Kong Kian-Keong Poh A review of COVID-19 vaccination and the reported cardiac manifestations Singapore Medical Journal cardiac side effects covid-19 myocarditis pericarditis vaccination |
| title | A review of COVID-19 vaccination and the reported cardiac manifestations |
| title_full | A review of COVID-19 vaccination and the reported cardiac manifestations |
| title_fullStr | A review of COVID-19 vaccination and the reported cardiac manifestations |
| title_full_unstemmed | A review of COVID-19 vaccination and the reported cardiac manifestations |
| title_short | A review of COVID-19 vaccination and the reported cardiac manifestations |
| title_sort | review of covid 19 vaccination and the reported cardiac manifestations |
| topic | cardiac side effects covid-19 myocarditis pericarditis vaccination |
| url | https://journals.lww.com/10.11622/smedj.2021210 |
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