Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.

<h4>Background</h4>The World Health Organization (WHO) released new Child Growth Standards in 2006 to replace the current National Center for Health Statistics (NCHS) growth reference. We assessed how switching from the NCHS to the newly released WHO Growth Standards affects the estimate...

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Main Authors: Marc-André Prost, Andreas Jahn, Sian Floyd, Hazzie Mvula, Eleneus Mwaiyeghele, Venance Mwinuka, Thomas Mhango, Amelia C Crampin, Nuala McGrath, Paul E M Fine, Judith R Glynn
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Language:English
Published: Public Library of Science (PLoS) 2008-07-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002684&type=printable
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author Marc-André Prost
Andreas Jahn
Sian Floyd
Hazzie Mvula
Eleneus Mwaiyeghele
Venance Mwinuka
Thomas Mhango
Amelia C Crampin
Nuala McGrath
Paul E M Fine
Judith R Glynn
author_facet Marc-André Prost
Andreas Jahn
Sian Floyd
Hazzie Mvula
Eleneus Mwaiyeghele
Venance Mwinuka
Thomas Mhango
Amelia C Crampin
Nuala McGrath
Paul E M Fine
Judith R Glynn
author_sort Marc-André Prost
collection DOAJ
description <h4>Background</h4>The World Health Organization (WHO) released new Child Growth Standards in 2006 to replace the current National Center for Health Statistics (NCHS) growth reference. We assessed how switching from the NCHS to the newly released WHO Growth Standards affects the estimated prevalence of wasting, underweight and stunting, and the pattern of risk factors identified.<h4>Methodology/principal findings</h4>Data were drawn from a village-informant driven Demographic Surveillance System in Northern Malawi. Children (n = 1328) were visited twice at 0-4 months and 11-15 months. Data were collected on the demographic and socio-economic environment of the child, health history, maternal and child anthropometry and child feeding practices. Weight-for-length, weight-for-age and length-for-age were derived in z-scores using the two growth references. In early infancy, prevalence estimates were 2.9, 6.1, and 8.5 fold higher for stunting, underweight, and wasting respectively using the WHO standards compared to NCHS reference (p<0.001 for all). At one year, prevalence estimates for wasting and stunting did not differ significantly according to reference used, but the prevalence of underweight was half that with the NCHS reference (p<0.001). Patterns of risk factors were similar with the two growth references for all outcomes at one year although the strength of association was higher with WHO standards.<h4>Conclusions/significance</h4>Differences in prevalence estimates differed in magnitude but not direction from previous studies. The scale of these differences depends on the population's nutritional status thus it should not be assumed a priori. The increase in estimated prevalence of wasting in early infancy has implications for feeding programs targeting lactating mothers and ante-natal multiple micronutrients supplementation to tackle small birth size. Risk factors identified using WHO standards remain comparable with findings based on the NCHS reference in similar settings. Further research should aim to identify whether the young infants additionally diagnosed as malnourished by this new standard are more appropriate targets for interventions than those identified with the NCHS reference.
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spelling doaj-art-cfcc170a1dfc4b96860e76146369e18d2025-08-20T02:38:28ZengPublic Library of Science (PLoS)PLoS ONE1932-62032008-07-0137e268410.1371/journal.pone.0002684Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.Marc-André ProstAndreas JahnSian FloydHazzie MvulaEleneus MwaiyegheleVenance MwinukaThomas MhangoAmelia C CrampinNuala McGrathPaul E M FineJudith R Glynn<h4>Background</h4>The World Health Organization (WHO) released new Child Growth Standards in 2006 to replace the current National Center for Health Statistics (NCHS) growth reference. We assessed how switching from the NCHS to the newly released WHO Growth Standards affects the estimated prevalence of wasting, underweight and stunting, and the pattern of risk factors identified.<h4>Methodology/principal findings</h4>Data were drawn from a village-informant driven Demographic Surveillance System in Northern Malawi. Children (n = 1328) were visited twice at 0-4 months and 11-15 months. Data were collected on the demographic and socio-economic environment of the child, health history, maternal and child anthropometry and child feeding practices. Weight-for-length, weight-for-age and length-for-age were derived in z-scores using the two growth references. In early infancy, prevalence estimates were 2.9, 6.1, and 8.5 fold higher for stunting, underweight, and wasting respectively using the WHO standards compared to NCHS reference (p<0.001 for all). At one year, prevalence estimates for wasting and stunting did not differ significantly according to reference used, but the prevalence of underweight was half that with the NCHS reference (p<0.001). Patterns of risk factors were similar with the two growth references for all outcomes at one year although the strength of association was higher with WHO standards.<h4>Conclusions/significance</h4>Differences in prevalence estimates differed in magnitude but not direction from previous studies. The scale of these differences depends on the population's nutritional status thus it should not be assumed a priori. The increase in estimated prevalence of wasting in early infancy has implications for feeding programs targeting lactating mothers and ante-natal multiple micronutrients supplementation to tackle small birth size. Risk factors identified using WHO standards remain comparable with findings based on the NCHS reference in similar settings. Further research should aim to identify whether the young infants additionally diagnosed as malnourished by this new standard are more appropriate targets for interventions than those identified with the NCHS reference.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002684&type=printable
spellingShingle Marc-André Prost
Andreas Jahn
Sian Floyd
Hazzie Mvula
Eleneus Mwaiyeghele
Venance Mwinuka
Thomas Mhango
Amelia C Crampin
Nuala McGrath
Paul E M Fine
Judith R Glynn
Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.
PLoS ONE
title Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.
title_full Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.
title_fullStr Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.
title_full_unstemmed Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.
title_short Implication of new WHO growth standards on identification of risk factors and estimated prevalence of malnutrition in rural Malawian infants.
title_sort implication of new who growth standards on identification of risk factors and estimated prevalence of malnutrition in rural malawian infants
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0002684&type=printable
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