Polymerized laminin-modified microcapsules improve pancreatic islet resilience towards cytokine induced inflammatory stress and lower chemoattractant cytokine secretion

Encapsulation of human pancreatic islets in semipermeable membranes offers a promising, less invasive alternative to whole pancreas transplantation for Type 1 Diabetes (T1D), potentially reducing the need for immunosuppressive drugs and improving graft survival. However, the inflammatory environment...

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Bibliographic Details
Main Authors: Isaura Beatriz Borges Silva, Theo Borghuis, Tian Qin, Mari Cleide Sogayar, Paul de Vos
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials Today Bio
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425003722
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