USP20 mediates malignant phenotypic changes in bladder cancer through direct interactions with YAP1

USP20 mediates malignant phenotypic changes in bladder cancer through direct interactions with YAP1

Yes-associated protein 1 (YAP1) has attracted attention for its potential in the treatment of various types of malignancies. The Hippo-YAP1 axis is inhibited in bladder cancer (BC), which is a major driver of BC progression and oncogenesis. Hippo pathway activity is controlled by the phosphorylation...

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Bibliographic Details
Main Authors: Wensun Chen, Siqi Wu, Yifan Chen, Weijian Li, Yiqing Cao, Yingchun Liang, Xiyu Dai, Xinan Chen, Yilin Chen, Tian Chen, Shenghua Liu, Chen Yang, Haowen Jiang
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Bladder cancer
YAP1
USP20
Malignant phenotype
deubiquitinase
Online Access:http://www.sciencedirect.com/science/article/pii/S147655862400143X
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