Expert consensus on intentional tooth replantation
Abstract Intentional tooth replantation (ITR) is an advanced treatment modality and the procedure of last resort for preserving teeth with inaccessible endodontic or resorptive lesions. ITR is defined as the deliberate extraction of a tooth; evaluation of the root surface, endodontic manipulation, a...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2025-03-01
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| Series: | International Journal of Oral Science |
| Online Access: | https://doi.org/10.1038/s41368-024-00337-5 |
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| author | Zhengmei Lin Dingming Huang Shuheng Huang Zhi Chen Qing Yu Benxiang Hou Lihong Qiu Wenxia Chen Jiyao Li Xiaoyan Wang Zhengwei Huang Jinhua Yu Jin Zhao Yihuai Pan Shuang Pan Deqin Yang Weidong Niu Qi Zhang Shuli Deng Jingzhi Ma Xiuping Meng Jian Yang Jiayuan Wu Lan Zhang Jin Zhang Xiaoli Xie Jinpu Chu Kehua Que Xuejun Ge Xiaojing Huang Zhe Ma Lin Yue Xuedong Zhou Junqi Ling |
| author_facet | Zhengmei Lin Dingming Huang Shuheng Huang Zhi Chen Qing Yu Benxiang Hou Lihong Qiu Wenxia Chen Jiyao Li Xiaoyan Wang Zhengwei Huang Jinhua Yu Jin Zhao Yihuai Pan Shuang Pan Deqin Yang Weidong Niu Qi Zhang Shuli Deng Jingzhi Ma Xiuping Meng Jian Yang Jiayuan Wu Lan Zhang Jin Zhang Xiaoli Xie Jinpu Chu Kehua Que Xuejun Ge Xiaojing Huang Zhe Ma Lin Yue Xuedong Zhou Junqi Ling |
| author_sort | Zhengmei Lin |
| collection | DOAJ |
| description | Abstract Intentional tooth replantation (ITR) is an advanced treatment modality and the procedure of last resort for preserving teeth with inaccessible endodontic or resorptive lesions. ITR is defined as the deliberate extraction of a tooth; evaluation of the root surface, endodontic manipulation, and repair; and placement of the tooth back into its original socket. Case reports, case series, cohort studies, and randomized controlled trials have demonstrated the efficacy of ITR in the retention of natural teeth that are untreatable or difficult to manage with root canal treatment or endodontic microsurgery. However, variations in clinical protocols for ITR exist due to the empirical nature of the original protocols and rapid advancements in the field of oral biology and dental materials. This heterogeneity in protocols may cause confusion among dental practitioners; therefore, guidelines and considerations for ITR should be explicated. This expert consensus discusses the biological foundation of ITR, the available clinical protocols and current status of ITR in treating teeth with refractory apical periodontitis or anatomical aberration, and the main complications of this treatment, aiming to refine the clinical management of ITR in accordance with the progress of basic research and clinical studies; the findings suggest that ITR may become a more consistent evidence-based option in dental treatment. |
| format | Article |
| id | doaj-art-cfc2d1126945469a84aac734f198aea8 |
| institution | DOAJ |
| issn | 2049-3169 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | International Journal of Oral Science |
| spelling | doaj-art-cfc2d1126945469a84aac734f198aea82025-08-20T03:05:52ZengNature Publishing GroupInternational Journal of Oral Science2049-31692025-03-0117111010.1038/s41368-024-00337-5Expert consensus on intentional tooth replantationZhengmei Lin0Dingming Huang1Shuheng Huang2Zhi Chen3Qing Yu4Benxiang Hou5Lihong Qiu6Wenxia Chen7Jiyao Li8Xiaoyan Wang9Zhengwei Huang10Jinhua Yu11Jin Zhao12Yihuai Pan13Shuang Pan14Deqin Yang15Weidong Niu16Qi Zhang17Shuli Deng18Jingzhi Ma19Xiuping Meng20Jian Yang21Jiayuan Wu22Lan Zhang23Jin Zhang24Xiaoli Xie25Jinpu Chu26Kehua Que27Xuejun Ge28Xiaojing Huang29Zhe Ma30Lin Yue31Xuedong Zhou32Junqi Ling33Department of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University & Guangdong Provincial Key Laboratory of StomatologyState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan UniversityDepartment of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University & Guangdong Provincial Key Laboratory of StomatologyState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan UniversityState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shanxi Key Laboratory of Oral Diseases, Department of Operative Dentistry & Endodontics, School of Stomatology, The Fourth Military Medical UniversityCenter for Microscope Enhanced Dentistry, Beijing Stomatological Hospital, Capital Medical UniversityDepartment of Endodontics, School of Stomatology, China Medical UniversityCollege & Hospital of Stomatology, Guangxi Medical UniversityState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan UniversityDepartment of Cariology and Endodontology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Peking UniversityDepartment of Endodontics, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, College of Stomatology, Shanghai Jiao Tong University, National Clinical Research Center for Oral Diseases, National Center for Stomatology, Shanghai Key Laboratory of StomatologyDepartment of Endodontics, Jiangsu Key Laboratory of Oral Diseases, Affiliated Hospital of Stomatology, Nanjing Medical UniversityDepartment of Endodontics, The First Affiliated Hospital of Xinjiang Medical UniversityDepartment of Endodontics, School and Hospital of Stomatology, Wenzhou Medical UniversityDepartment of Endodontics, The First Affiliated Hospital of Harbin Medical University & Department of Endodontics, School of Stomatology, Harbin Medical UniversityDepartment of Conservative Dentistry and Endodontics, Shanghai Stomatological Hospital & School of Stomatology, Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan UniversitySchool of Stomatology, Dalian Medical UniversityDepartment of Endodontics, Stomatological Hospital and Dental School of Tongji University, Shanghai Engineering Research Center of Tooth Restoration and RegenerationStomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang UniversityDepartment of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyHospital of Stomatology, Jilin UniversityDepartment of Endodontics, The Affiliated Stomatological Hospital of Nanchang UniversityKey Laboratory of Oral Disease Research, School of Stomatology, Zunyi Medical UniversityState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan UniversityShandong University, School of StomatologyDepartment of Endodontology, Hunan Xiangya Stomatological Hospital, Central South UniversityThe First Affiliated Hospital of Zhengzhou UniversityDepartment of Endodontics, College of Stomatology, Tianjin Medical UniversityShanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of StomatologyFujian Key Laboratory of Oral Disease & Fujian Provincial Engineering Research Center of Oral Biomaterial & Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology, Fujian Medical UniversityDepartment of Preventive Dentistry, Hebei Key Laboratory of Stomatology, Hebei Clinical Research Center for Oral Diseases, School and Hospital of Stomatology, Hebei Medical University, ShijiazhuangDepartment of Cariology and Endodontology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Peking UniversityState Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan UniversityDepartment of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University & Guangdong Provincial Key Laboratory of StomatologyAbstract Intentional tooth replantation (ITR) is an advanced treatment modality and the procedure of last resort for preserving teeth with inaccessible endodontic or resorptive lesions. ITR is defined as the deliberate extraction of a tooth; evaluation of the root surface, endodontic manipulation, and repair; and placement of the tooth back into its original socket. Case reports, case series, cohort studies, and randomized controlled trials have demonstrated the efficacy of ITR in the retention of natural teeth that are untreatable or difficult to manage with root canal treatment or endodontic microsurgery. However, variations in clinical protocols for ITR exist due to the empirical nature of the original protocols and rapid advancements in the field of oral biology and dental materials. This heterogeneity in protocols may cause confusion among dental practitioners; therefore, guidelines and considerations for ITR should be explicated. This expert consensus discusses the biological foundation of ITR, the available clinical protocols and current status of ITR in treating teeth with refractory apical periodontitis or anatomical aberration, and the main complications of this treatment, aiming to refine the clinical management of ITR in accordance with the progress of basic research and clinical studies; the findings suggest that ITR may become a more consistent evidence-based option in dental treatment.https://doi.org/10.1038/s41368-024-00337-5 |
| spellingShingle | Zhengmei Lin Dingming Huang Shuheng Huang Zhi Chen Qing Yu Benxiang Hou Lihong Qiu Wenxia Chen Jiyao Li Xiaoyan Wang Zhengwei Huang Jinhua Yu Jin Zhao Yihuai Pan Shuang Pan Deqin Yang Weidong Niu Qi Zhang Shuli Deng Jingzhi Ma Xiuping Meng Jian Yang Jiayuan Wu Lan Zhang Jin Zhang Xiaoli Xie Jinpu Chu Kehua Que Xuejun Ge Xiaojing Huang Zhe Ma Lin Yue Xuedong Zhou Junqi Ling Expert consensus on intentional tooth replantation International Journal of Oral Science |
| title | Expert consensus on intentional tooth replantation |
| title_full | Expert consensus on intentional tooth replantation |
| title_fullStr | Expert consensus on intentional tooth replantation |
| title_full_unstemmed | Expert consensus on intentional tooth replantation |
| title_short | Expert consensus on intentional tooth replantation |
| title_sort | expert consensus on intentional tooth replantation |
| url | https://doi.org/10.1038/s41368-024-00337-5 |
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