Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake
Vitamin C (ascorbic acid: AA) uptake in neurons occurs via the sodium-dependent vitamin C transporter-2 (SVCT2), which is highly expressed in the central nervous system (CNS). During chronic neuroinflammation or infection, CNS levels of lipopolysaccharide (LPS) and LPS-induced tumor necrosis factor-...
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Main Authors: | Veedamali S. Subramanian, Trevor Teafatiller, Anshu Agrawal, Masashi Kitazawa, Jonathan S. Marchant |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2021/4157132 |
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