Calcium-dependent pathway as a primary cause of hypoxic RGC damage in monkey retinal explants.

<h4>Purpose</h4>Retinal ganglion cells (RGCs) loss or degeneration in the retina is a hallmark of many sight-threatening diseases, including glaucoma and retinopathy. In our previous studies, calcium-activated cysteine protease calpain induced RGC damage under hypoxia/reoxygenation in th...

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Bibliographic Details
Main Authors: Emi Nakajima, Momoko Otsugu-Kobayashi, Takatoshi Uchida, Kana Orihara, Thomas R Shearer, Mitsuyoshi Azuma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0327246
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