Calcium-dependent pathway as a primary cause of hypoxic RGC damage in monkey retinal explants.
<h4>Purpose</h4>Retinal ganglion cells (RGCs) loss or degeneration in the retina is a hallmark of many sight-threatening diseases, including glaucoma and retinopathy. In our previous studies, calcium-activated cysteine protease calpain induced RGC damage under hypoxia/reoxygenation in th...
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| Main Authors: | Emi Nakajima, Momoko Otsugu-Kobayashi, Takatoshi Uchida, Kana Orihara, Thomas R Shearer, Mitsuyoshi Azuma |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0327246 |
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