Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction

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Main Authors: Gonzalo P. Solis, Federica Rachele Danti, Yonika A. Larasati, Federica Graziola, Carolina Croci, Elisa Osanni, Alexey Koval, Giovanna Zorzi, Vladimir L. Katanaev
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Genes and Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S235230422500011X
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author Gonzalo P. Solis
Federica Rachele Danti
Yonika A. Larasati
Federica Graziola
Carolina Croci
Elisa Osanni
Alexey Koval
Giovanna Zorzi
Vladimir L. Katanaev
author_facet Gonzalo P. Solis
Federica Rachele Danti
Yonika A. Larasati
Federica Graziola
Carolina Croci
Elisa Osanni
Alexey Koval
Giovanna Zorzi
Vladimir L. Katanaev
author_sort Gonzalo P. Solis
collection DOAJ
format Article
id doaj-art-cfbee1e44ddf42b68f37d7a26c1395ee
institution Kabale University
issn 2352-3042
language English
publishDate 2025-09-01
publisher KeAi Communications Co., Ltd.
record_format Article
series Genes and Diseases
spelling doaj-art-cfbee1e44ddf42b68f37d7a26c1395ee2025-08-20T03:29:15ZengKeAi Communications Co., Ltd.Genes and Diseases2352-30422025-09-0112510152210.1016/j.gendis.2025.101522Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunctionGonzalo P. Solis0Federica Rachele Danti1Yonika A. Larasati2Federica Graziola3Carolina Croci4Elisa Osanni5Alexey Koval6Giovanna Zorzi7Vladimir L. Katanaev8Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva 1211, SwitzerlandChild Neuropsychiatry Unit, Department of Pediatric Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano 20133, ItalyTranslational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva 1211, SwitzerlandChild Neuropsychiatry Unit, Department of Pediatric Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano 20133, ItalyChild Neuropsychiatry and Child and Adolescent Psychology, Department of Mental Health and Pathological Addiction, AUSL Piacenza, Piacenza 29121, ItalyScientific Institute, IRCCS E. Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano, Treviso 31015, ItalyTranslational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva 1211, SwitzerlandChild Neuropsychiatry Unit, Department of Pediatric Neuroscience, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano 20133, Italy; Corresponding author.Translational Research Center in Oncohaematology, Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva 1211, Switzerland; Corresponding author.http://www.sciencedirect.com/science/article/pii/S235230422500011X
spellingShingle Gonzalo P. Solis
Federica Rachele Danti
Yonika A. Larasati
Federica Graziola
Carolina Croci
Elisa Osanni
Alexey Koval
Giovanna Zorzi
Vladimir L. Katanaev
Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction
Genes and Diseases
title Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction
title_full Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction
title_fullStr Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction
title_full_unstemmed Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction
title_short Clinical-molecular profiling of atypical GNAO1 patients: Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction
title_sort clinical molecular profiling of atypical gnao1 patients novel pathogenic variants unusual manifestations and severe molecular dysfunction
url http://www.sciencedirect.com/science/article/pii/S235230422500011X
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