Pancancer analysis of DNA damage repair gene mutations and their impact on immune regulatory gene expression

Abstract DNA damage is a key factor in many human disorders, including cancer, chronic inflammation, and early aging. Genes involved in DNA damage repair (DDR) not only maintain genomic stability but also contribute to immune responses by regulating the expression of antimicrobial peptides and ligan...

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Bibliographic Details
Main Authors: Kanchana Yadav, Trishala Das, Andrew M. Lynn
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-99965-y
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