Pancancer analysis of DNA damage repair gene mutations and their impact on immune regulatory gene expression
Abstract DNA damage is a key factor in many human disorders, including cancer, chronic inflammation, and early aging. Genes involved in DNA damage repair (DDR) not only maintain genomic stability but also contribute to immune responses by regulating the expression of antimicrobial peptides and ligan...
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| Main Authors: | Kanchana Yadav, Trishala Das, Andrew M. Lynn |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-99965-y |
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