Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signalling and drug detoxification and are essential for parasite survival.
Cholinesterase (ChE) function in schistosomes is essential for orchestration of parasite neurotransmission but has been poorly defined with respect to the molecules responsible. Interrogation of the S. mansoni genome has revealed the presence of three ChE domain-containing genes (Smche)s, which we h...
Saved in:
| Main Authors: | Bemnet A Tedla, Javier Sotillo, Darren Pickering, Ramon M Eichenberger, Stephanie Ryan, Luke Becker, Alex Loukas, Mark S Pearson |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2019-12-01
|
| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1008213&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effects of proteasome inhibitor MG-132 on the parasite Schistosoma mansoni.
by: Enyara R Morais, et al.
Published: (2017-01-01) -
Introduction of epigenetic variation contribute to resistance against the human parasite Schistosoma mansoni
by: Nelia Luviano-Aparicio, et al.
Published: (2025-07-01) -
Fatty acid oxidation is essential for egg production by the parasitic flatworm Schistosoma mansoni.
by: Stanley Ching-Cheng Huang, et al.
Published: (2012-01-01) -
TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoni.
by: Tori C Freitas, et al.
Published: (2007-04-01) -
Acute encephalitis caused by Schistosoma mansoni
by: Paulo P. Christo, et al.
Published: (2010-12-01)