PIEZO1 activity promotes stemness in mesenchymal stem cells under shear stress and enhances protection of leukemia cells
Abstract Mesenchymal stem cells (MSCs) differentiate into cells of multiple lineages and play an essential role in bone formation, tissue regeneration, immunomodulation and are also necessary to maintain hematopoiesis in bone marrow. The lineage commitment of MSCs into osteoblasts is controlled by s...
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| Main Authors: | Amit Sharma, Jina Bhattacharyya, Piruthivi Sukumar, Bithiah Grace Jaganathan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-09549-z |
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