A model of varicella-zoster reactivation
Mathematical models have been used to study the dynamic interaction of many infectious diseases with the host's immune system. In this paper, we study Varicella Zoster Virus, which is responsible for chicken pox (varicella), and after a long period of latency, herpes zoster (shingles). After...
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| Format: | Article |
| Language: | English |
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AIMS Press
2010-09-01
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| Series: | Mathematical Biosciences and Engineering |
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| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.765 |
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| _version_ | 1832590217558622208 |
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| author | Jonathan E. Forde Bailey Meeker |
| author_facet | Jonathan E. Forde Bailey Meeker |
| author_sort | Jonathan E. Forde |
| collection | DOAJ |
| description | Mathematical models have been used to study the dynamic interaction of many infectious diseases with the host's immune system. In this paper, we study Varicella Zoster Virus, which is responsible for chicken pox (varicella), and after a long period of latency, herpes zoster (shingles). After developing the model and demonstrating that is exhibits the type of periodic behavior necessary for long term latency and reactivation, we examine the implications of the model for vaccine booster programs aimed at preventing herpes zoster. |
| format | Article |
| id | doaj-art-cf97c89f513043a48aea4af345755cdc |
| institution | Kabale University |
| issn | 1551-0018 |
| language | English |
| publishDate | 2010-09-01 |
| publisher | AIMS Press |
| record_format | Article |
| series | Mathematical Biosciences and Engineering |
| spelling | doaj-art-cf97c89f513043a48aea4af345755cdc2025-01-24T02:00:58ZengAIMS PressMathematical Biosciences and Engineering1551-00182010-09-017476577710.3934/mbe.2010.7.765A model of varicella-zoster reactivationJonathan E. Forde0Bailey Meeker1Department of Mathematics and Computer Science, Hobart and William Smith Colleges, Geneva, NY 14456Department of Mathematics and Computer Science, Hobart and William Smith Colleges, Geneva, NY 14456Mathematical models have been used to study the dynamic interaction of many infectious diseases with the host's immune system. In this paper, we study Varicella Zoster Virus, which is responsible for chicken pox (varicella), and after a long period of latency, herpes zoster (shingles). After developing the model and demonstrating that is exhibits the type of periodic behavior necessary for long term latency and reactivation, we examine the implications of the model for vaccine booster programs aimed at preventing herpes zoster.https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.765mathematical model.periodic solutionslatencyvaccine boostervzvchronic infection |
| spellingShingle | Jonathan E. Forde Bailey Meeker A model of varicella-zoster reactivation Mathematical Biosciences and Engineering mathematical model. periodic solutions latency vaccine booster vzv chronic infection |
| title | A model of varicella-zoster reactivation |
| title_full | A model of varicella-zoster reactivation |
| title_fullStr | A model of varicella-zoster reactivation |
| title_full_unstemmed | A model of varicella-zoster reactivation |
| title_short | A model of varicella-zoster reactivation |
| title_sort | model of varicella zoster reactivation |
| topic | mathematical model. periodic solutions latency vaccine booster vzv chronic infection |
| url | https://www.aimspress.com/article/doi/10.3934/mbe.2010.7.765 |
| work_keys_str_mv | AT jonathaneforde amodelofvaricellazosterreactivation AT baileymeeker amodelofvaricellazosterreactivation AT jonathaneforde modelofvaricellazosterreactivation AT baileymeeker modelofvaricellazosterreactivation |