Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices
In response to growing environmental concerns, the scientific community is increasingly incorporating green chemistry principles into modern analytical techniques. Electrochemical paper-based analytical devices (ePADs) have emerged as a sustainable and efficient alternative to conventional analytica...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-11-01
|
| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/14/11/561 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850145610019110912 |
|---|---|
| author | Zarfashan Shahid Kornautchaya Veenuttranon Xianbo Lu Jiping Chen |
| author_facet | Zarfashan Shahid Kornautchaya Veenuttranon Xianbo Lu Jiping Chen |
| author_sort | Zarfashan Shahid |
| collection | DOAJ |
| description | In response to growing environmental concerns, the scientific community is increasingly incorporating green chemistry principles into modern analytical techniques. Electrochemical paper-based analytical devices (ePADs) have emerged as a sustainable and efficient alternative to conventional analytical devices, offering robust applications in point-of-care testing, personalized healthcare, environmental monitoring, and food safety. ePADs align with green chemistry by minimizing reagent use, reducing energy consumption, and being disposable, making them ideal for eco-friendly and cost-effective analyses. Their user-friendly interface, alongside sensitive and selective detection capabilities, has driven their popularity in recent years. This review traces the evolution of ePADs from simple designs to complex multilayered structures that optimize analyte flow and improve detection. It also delves into innovative electrode fabrication methods, assessing key advantages, limitations, and modification strategies for enhanced sensitivity. Application-focused sections explore recent advancements in using ePADs for detecting diseases, monitoring environmental hazards like heavy metals and bacterial contamination, and screening contaminants in food. The integration of cutting-edge technologies, such as wearable wireless devices and the Internet of Things (IoT), further positions ePADs at the forefront of point-of-care testing (POCT). Finally, the review identifies key research gaps and proposes future directions for the field. |
| format | Article |
| id | doaj-art-cf7ef121de054a40906c41ae678c5ce9 |
| institution | OA Journals |
| issn | 2079-6374 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj-art-cf7ef121de054a40906c41ae678c5ce92025-08-20T02:28:03ZengMDPI AGBiosensors2079-63742024-11-01141156110.3390/bios14110561Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical DevicesZarfashan Shahid0Kornautchaya Veenuttranon1Xianbo Lu2Jiping Chen3CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, ChinaCAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, ChinaCAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, ChinaCAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, ChinaIn response to growing environmental concerns, the scientific community is increasingly incorporating green chemistry principles into modern analytical techniques. Electrochemical paper-based analytical devices (ePADs) have emerged as a sustainable and efficient alternative to conventional analytical devices, offering robust applications in point-of-care testing, personalized healthcare, environmental monitoring, and food safety. ePADs align with green chemistry by minimizing reagent use, reducing energy consumption, and being disposable, making them ideal for eco-friendly and cost-effective analyses. Their user-friendly interface, alongside sensitive and selective detection capabilities, has driven their popularity in recent years. This review traces the evolution of ePADs from simple designs to complex multilayered structures that optimize analyte flow and improve detection. It also delves into innovative electrode fabrication methods, assessing key advantages, limitations, and modification strategies for enhanced sensitivity. Application-focused sections explore recent advancements in using ePADs for detecting diseases, monitoring environmental hazards like heavy metals and bacterial contamination, and screening contaminants in food. The integration of cutting-edge technologies, such as wearable wireless devices and the Internet of Things (IoT), further positions ePADs at the forefront of point-of-care testing (POCT). Finally, the review identifies key research gaps and proposes future directions for the field.https://www.mdpi.com/2079-6374/14/11/561electrochemical paper-based analytical devices (ePADs)microfluidic paper-based analytical devices (μPAD)biosensorsclinical diagnosisfood analysisenvironmental monitoring |
| spellingShingle | Zarfashan Shahid Kornautchaya Veenuttranon Xianbo Lu Jiping Chen Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices Biosensors electrochemical paper-based analytical devices (ePADs) microfluidic paper-based analytical devices (μPAD) biosensors clinical diagnosis food analysis environmental monitoring |
| title | Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices |
| title_full | Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices |
| title_fullStr | Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices |
| title_full_unstemmed | Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices |
| title_short | Recent Advances in the Fabrication and Application of Electrochemical Paper-Based Analytical Devices |
| title_sort | recent advances in the fabrication and application of electrochemical paper based analytical devices |
| topic | electrochemical paper-based analytical devices (ePADs) microfluidic paper-based analytical devices (μPAD) biosensors clinical diagnosis food analysis environmental monitoring |
| url | https://www.mdpi.com/2079-6374/14/11/561 |
| work_keys_str_mv | AT zarfashanshahid recentadvancesinthefabricationandapplicationofelectrochemicalpaperbasedanalyticaldevices AT kornautchayaveenuttranon recentadvancesinthefabricationandapplicationofelectrochemicalpaperbasedanalyticaldevices AT xianbolu recentadvancesinthefabricationandapplicationofelectrochemicalpaperbasedanalyticaldevices AT jipingchen recentadvancesinthefabricationandapplicationofelectrochemicalpaperbasedanalyticaldevices |