International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study
Background Acute exacerbations of asthma are common in children, however, treatment decisions for severe exacerbations are challenging due to a lack of robust evidence. In order to create more robust research, a core set of outcome measures needs to be developed. In developing these outcomes, it is...
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BMJ Publishing Group
2023-07-01
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| Series: | BMJ Open Respiratory Research |
| Online Access: | https://bmjopenrespres.bmj.com/content/10/1/e001502.full |
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| author | Franz E Babl Ricardo M Fernandes Charmaine S Gray Colin V E Powell Simon Craig Javier Benito Yao Xu Mark D Lyttle Damian Roland Suzanne Schuh Stuart Dalziel Jenny Couper Shu-Ling Chong Mike Johnson Indumathy Santhanam Baljit Cheema Adriana Yock-Corrales |
| author_facet | Franz E Babl Ricardo M Fernandes Charmaine S Gray Colin V E Powell Simon Craig Javier Benito Yao Xu Mark D Lyttle Damian Roland Suzanne Schuh Stuart Dalziel Jenny Couper Shu-Ling Chong Mike Johnson Indumathy Santhanam Baljit Cheema Adriana Yock-Corrales |
| author_sort | Franz E Babl |
| collection | DOAJ |
| description | Background Acute exacerbations of asthma are common in children, however, treatment decisions for severe exacerbations are challenging due to a lack of robust evidence. In order to create more robust research, a core set of outcome measures needs to be developed. In developing these outcomes, it is important to understand the views of clinicians who care for these children in particular, views that relate to outcome measures and research priorities.Methods To determine the views of clinicians, a total of 26 semistructured interviews based on the theoretical domains framework were conducted. These included experienced clinicians from emergency, intensive care and inpatient paediatrics across 17 countries. The interviews were recorded, and later transcribed. All data analyses were conducted in Nvivo by using thematic analysis.Results The length of stay in hospital and patient-focused parameters, such as timing to return to school and normal activity, were the most frequently highlighted outcome measures, with clinicians identifying the need to achieve a consensus on key core outcome measure sets. Most research questions focused on understanding the best treatment options, including the role of novel therapies and respiratory support.Conclusion Our study provides an insight into what research questions and outcome measures clinicians view as important. In addition, information on how clinicians define asthma severity and measure treatment success will assist with methodological design in future trials. The current findings will be used in parallel with a further Paediatric Emergency Research Network study focusing on the child and family perspectives and will contribute to develop a core outcome set for future research. |
| format | Article |
| id | doaj-art-cf78f431b5df479abb27b0af4c484ef4 |
| institution | DOAJ |
| issn | 2052-4439 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Respiratory Research |
| spelling | doaj-art-cf78f431b5df479abb27b0af4c484ef42025-08-20T03:02:02ZengBMJ Publishing GroupBMJ Open Respiratory Research2052-44392023-07-0110110.1136/bmjresp-2022-001502International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview studyFranz E Babl0Ricardo M Fernandes1Charmaine S Gray2Colin V E Powell3Simon Craig4Javier Benito5Yao Xu6Mark D Lyttle7Damian Roland8Suzanne Schuh9Stuart Dalziel10Jenny Couper11Shu-Ling Chong12Mike Johnson13Indumathy Santhanam14Baljit Cheema15Adriana Yock-Corrales165 Emergency Department, The Royal Children`s Hospital Melbourne, Melbourne, Victoria, AustraliaDepartment of Pediatrics, Hospital de Santa Maria, Lisboa, PortugalPaediatric Emergency Department, Flinders Medical Centre, Bedford Park, South Australia, AustraliaDivision of Population Medicine, School of Medicine, Cardiff University, Cardiff, UKDepartment of Emergency Medicine, Monash Medical Centre, Clayton, Victoria, AustraliaPediatric Emergency Department, Cruces University Hospital, Basque Health Service, Biobizkaia Health Research Institute, Barakaldo, SpainDepartment of Paediatrics, School of Clinical Sciences, Monash University, Clayton, Victoria, AustraliaResearch in Emergency Care Avon Collaborative Hub (REACH), University of the West of England, Bristol, UKPaediatric Emergency Medicine Leicester Academic (PEMLA) Group, Children’s Emergency Department, Leicester Royal Infirmary, Leicester, UK13 Division of Pediatric Emergency Medicine, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, CanadaSurgery and Paediatrics, The University of Auckland Faculty of Health and Medical Sciences, Auckland, New ZealandAdelaide Medical School, Discipline of Paediatrics, The University of Adelaide, Adelaide, South Australia, AustraliaDepartment of Emergency Medicine, KK Women`s and Children`s Hospital, SingHealth Paediatrics Academic Clinical Programme, Singapore20 Department of Pediatrics, Division of Pediatric Emergency Medicine, The University of Utah School of Medicine, Salt Lake City, Utah, USA27 National Health Mission, Tamil Nadu, India29 Department of Paediatrics & Child Health, University of Cape Town Faculty of Health Sciences, Western Cape, South Africa26 Department of Emergency, Hospital Nacional de Ninos Dr Carlos Saenz Herrera, C.C.S.S, San Jose, Costa RicaBackground Acute exacerbations of asthma are common in children, however, treatment decisions for severe exacerbations are challenging due to a lack of robust evidence. In order to create more robust research, a core set of outcome measures needs to be developed. In developing these outcomes, it is important to understand the views of clinicians who care for these children in particular, views that relate to outcome measures and research priorities.Methods To determine the views of clinicians, a total of 26 semistructured interviews based on the theoretical domains framework were conducted. These included experienced clinicians from emergency, intensive care and inpatient paediatrics across 17 countries. The interviews were recorded, and later transcribed. All data analyses were conducted in Nvivo by using thematic analysis.Results The length of stay in hospital and patient-focused parameters, such as timing to return to school and normal activity, were the most frequently highlighted outcome measures, with clinicians identifying the need to achieve a consensus on key core outcome measure sets. Most research questions focused on understanding the best treatment options, including the role of novel therapies and respiratory support.Conclusion Our study provides an insight into what research questions and outcome measures clinicians view as important. In addition, information on how clinicians define asthma severity and measure treatment success will assist with methodological design in future trials. The current findings will be used in parallel with a further Paediatric Emergency Research Network study focusing on the child and family perspectives and will contribute to develop a core outcome set for future research.https://bmjopenrespres.bmj.com/content/10/1/e001502.full |
| spellingShingle | Franz E Babl Ricardo M Fernandes Charmaine S Gray Colin V E Powell Simon Craig Javier Benito Yao Xu Mark D Lyttle Damian Roland Suzanne Schuh Stuart Dalziel Jenny Couper Shu-Ling Chong Mike Johnson Indumathy Santhanam Baljit Cheema Adriana Yock-Corrales International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study BMJ Open Respiratory Research |
| title | International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study |
| title_full | International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study |
| title_fullStr | International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study |
| title_full_unstemmed | International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study |
| title_short | International perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma: a qualitative interview study |
| title_sort | international perspective on research priorities and outcome measures of importance in the care of children with acute exacerbations of asthma a qualitative interview study |
| url | https://bmjopenrespres.bmj.com/content/10/1/e001502.full |
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