EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS
Monosodium glutamate (MSG) is widely consumed as food preservative and flavor enhancer. MSG administration in rats has been reported to induce oxidative stress causing damage to ovarian histological structures by affecting number of follicles and production of reproductive hormones. Polyphenols in...
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| Language: | English |
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Baqai University Press
2024-10-01
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| Series: | Baqai Journal of Health Sciences |
| Online Access: | https://journals.baqai.edu.pk/index.php/CS/article/view/85 |
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| author | Syami Yulianti et al |
| author_facet | Syami Yulianti et al |
| author_sort | Syami Yulianti et al |
| collection | DOAJ |
| description |
Monosodium glutamate (MSG) is widely consumed as food preservative and flavor enhancer. MSG
administration in rats has been reported to induce oxidative stress causing damage to ovarian histological
structures by affecting number of follicles and production of reproductive hormones. Polyphenols in green
tea are suggested as powerful antioxidants that inhibit free radicals responsible for causing oxidative stress.
This study aimed to investigate the effects of various doses of green tea on the Graafian follicles and serum
17b-estradiol levels in rats exposed to MSG. The design of this study was the post test only control group
experiment. A total of twenty-five white female rats (Rattus norvegicus) were divided into 5 treatment
groups. MSG in a dose of 0.7 mg/g body weight (BW) and green tea extract (Camellia sinensis) in doses
of 0.7, 1.4, and 2.8 mg/day were administered orally over 30 day period starting after the rats proestrus
phase. Graafian follicles were counted using light microscope while serum 17b-estradiol level was measured
using ELISA kit and the data was statistically analyzed using one-way ANOVA. A significant difference
of Graafian follicles number (p<0.04) and serum 17b-estradiol level (p<0.006) was observed across the
treatment groups. The results showed that green tea extract at a dose of 1.4 mg/day significantly increased
the number of Graafian follicles and serum 17b-estradiol level in female white rats exposed to MSG.
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| format | Article |
| id | doaj-art-cf7245db7d1d4e15b7dda704535e876d |
| institution | Kabale University |
| issn | 2312-4423 2312-6884 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Baqai University Press |
| record_format | Article |
| series | Baqai Journal of Health Sciences |
| spelling | doaj-art-cf7245db7d1d4e15b7dda704535e876d2025-02-11T18:45:42ZengBaqai University PressBaqai Journal of Health Sciences2312-44232312-68842024-10-01212EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATSSyami Yulianti et al Monosodium glutamate (MSG) is widely consumed as food preservative and flavor enhancer. MSG administration in rats has been reported to induce oxidative stress causing damage to ovarian histological structures by affecting number of follicles and production of reproductive hormones. Polyphenols in green tea are suggested as powerful antioxidants that inhibit free radicals responsible for causing oxidative stress. This study aimed to investigate the effects of various doses of green tea on the Graafian follicles and serum 17b-estradiol levels in rats exposed to MSG. The design of this study was the post test only control group experiment. A total of twenty-five white female rats (Rattus norvegicus) were divided into 5 treatment groups. MSG in a dose of 0.7 mg/g body weight (BW) and green tea extract (Camellia sinensis) in doses of 0.7, 1.4, and 2.8 mg/day were administered orally over 30 day period starting after the rats proestrus phase. Graafian follicles were counted using light microscope while serum 17b-estradiol level was measured using ELISA kit and the data was statistically analyzed using one-way ANOVA. A significant difference of Graafian follicles number (p<0.04) and serum 17b-estradiol level (p<0.006) was observed across the treatment groups. The results showed that green tea extract at a dose of 1.4 mg/day significantly increased the number of Graafian follicles and serum 17b-estradiol level in female white rats exposed to MSG. https://journals.baqai.edu.pk/index.php/CS/article/view/85 |
| spellingShingle | Syami Yulianti et al EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS Baqai Journal of Health Sciences |
| title | EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS |
| title_full | EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS |
| title_fullStr | EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS |
| title_full_unstemmed | EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS |
| title_short | EFFECTS OF GREEN TEA EXTRACT ON GRAAFIAN FOLLICLES AND SERUM17b-ESTRADIOL IN MONOSODIUM GLUTAMATE-EXPOSED RATS |
| title_sort | effects of green tea extract on graafian follicles and serum17b estradiol in monosodium glutamate exposed rats |
| url | https://journals.baqai.edu.pk/index.php/CS/article/view/85 |
| work_keys_str_mv | AT syamiyuliantietal effectsofgreenteaextractongraafianfolliclesandserum17bestradiolinmonosodiumglutamateexposedrats |