Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021

Introduction: The department of Cauca, Colombia, is endemic for dengue fever. The prevalence of severe dengue has consistently exceeded national indicators, highlighting the critical importance of appropriate and timely classification and treatment of patients according to dengue types. Objectives:...

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Main Authors: Bolaños-Díaz, María Cristina, López-Delgado, Darío Sebastian, Arango-Luque, Adriana, Polanco-Pasaje, Jhon Edwin
Format: Article
Language:Spanish
Published: Universidad de Antioquia 2025-04-01
Series:Iatreia
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Online Access:https://revistas.udea.edu.co/index.php/iatreia/article/view/356476
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author Bolaños-Díaz, María Cristina
López-Delgado, Darío Sebastian
Arango-Luque, Adriana
Polanco-Pasaje, Jhon Edwin
author_facet Bolaños-Díaz, María Cristina
López-Delgado, Darío Sebastian
Arango-Luque, Adriana
Polanco-Pasaje, Jhon Edwin
author_sort Bolaños-Díaz, María Cristina
collection DOAJ
description Introduction: The department of Cauca, Colombia, is endemic for dengue fever. The prevalence of severe dengue has consistently exceeded national indicators, highlighting the critical importance of appropriate and timely classification and treatment of patients according to dengue types. Objectives: To determine the sociodemographic and clinical factors associated with severe dengue in the department of Cauca from 2015 to 2021. Methods: An observational, analytical, retrospective cross-sectional study was conducted with a population of 4,048 dengue cases. Statistically significant variables were entered into a logistic regression model. Results: Of all cases, 98.5% (n=3,987) were classified as dengue fever. Factors associated with severe dengue included: days elapsed until medical consultation (OR 5.2; 95% CI: 2.1–12.5), hypotension (OR 3.8; 95% CI: 1.3– 10.9), hepatomegaly (OR 3.2; 95% CI: 1.4–7.3), mucosal hemorrhage (OR 2.3; 95% CI: 1.2–4.6), platelet count below 100,000 (OR 3.4; 95% CI: 1.7–6.8), and fluid accumulation (OR 6.5; 95% CI: 2.6–16.2). Conclusions: This study emphasizes the importance of comprehensive evaluation of dengue patients as a measure for early detection of warning signs and prevention of complications.
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spelling doaj-art-cf6f2a79bb7744aaa813ee7b2c30ccbd2025-08-20T02:09:01ZspaUniversidad de AntioquiaIatreia0121-07932011-79652025-04-0138224025310.17533/udea.iatreia.315Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021Bolaños-Díaz, María Cristina0https://orcid.org/0000-0003-1589-7378López-Delgado, Darío Sebastian1https://orcid.org/0000-0001-9826-6314Arango-Luque, Adriana2https://orcid.org/0000-0002-2953-2225Polanco-Pasaje, Jhon Edwin3https://orcid.org/0000-0002-7497-5607Secretaría de Salud Departamental del Cauca, Popayán, ColombiaUniversidad Cooperativa de Colombia, Pasto, ColombiaFundación Universitaria del Areandina, Bogotá, ColombiaUniversidad del Cauca, Popayán, ColombiaIntroduction: The department of Cauca, Colombia, is endemic for dengue fever. The prevalence of severe dengue has consistently exceeded national indicators, highlighting the critical importance of appropriate and timely classification and treatment of patients according to dengue types. Objectives: To determine the sociodemographic and clinical factors associated with severe dengue in the department of Cauca from 2015 to 2021. Methods: An observational, analytical, retrospective cross-sectional study was conducted with a population of 4,048 dengue cases. Statistically significant variables were entered into a logistic regression model. Results: Of all cases, 98.5% (n=3,987) were classified as dengue fever. Factors associated with severe dengue included: days elapsed until medical consultation (OR 5.2; 95% CI: 2.1–12.5), hypotension (OR 3.8; 95% CI: 1.3– 10.9), hepatomegaly (OR 3.2; 95% CI: 1.4–7.3), mucosal hemorrhage (OR 2.3; 95% CI: 1.2–4.6), platelet count below 100,000 (OR 3.4; 95% CI: 1.7–6.8), and fluid accumulation (OR 6.5; 95% CI: 2.6–16.2). Conclusions: This study emphasizes the importance of comprehensive evaluation of dengue patients as a measure for early detection of warning signs and prevention of complications.https://revistas.udea.edu.co/index.php/iatreia/article/view/356476denguedengue virussevere dengue
spellingShingle Bolaños-Díaz, María Cristina
López-Delgado, Darío Sebastian
Arango-Luque, Adriana
Polanco-Pasaje, Jhon Edwin
Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021
Iatreia
dengue
dengue virus
severe dengue
title Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021
title_full Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021
title_fullStr Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021
title_full_unstemmed Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021
title_short Factors associated with severe dengue in patients from Cauca, Colombia, 2015–2021
title_sort factors associated with severe dengue in patients from cauca colombia 2015 2021
topic dengue
dengue virus
severe dengue
url https://revistas.udea.edu.co/index.php/iatreia/article/view/356476
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AT arangoluqueadriana factorsassociatedwithseveredengueinpatientsfromcaucacolombia20152021
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