Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review

Introduction: Ketogenic and low-carbohydrate diets are characterized by a significant reduction in daily carbohydrate intake, resulting in ketone bodies becoming an alternative energy source to glucose. Studies over the past decade have confirmed the therapeutic potential of the ketogenic diet in s...

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Main Authors: Dominika Bąk, Julia Buszek, Piotr Czerniak, Adrianna Antoszewska, Weronika Bargiel, Halszka Wajdowicz, Mateusz Warzocha, Aldona Sokołowska
Format: Article
Language:English
Published: Kazimierz Wielki University 2025-06-01
Series:Journal of Education, Health and Sport
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Online Access:https://apcz.umk.pl/JEHS/article/view/60329
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author Dominika Bąk
Julia Buszek
Piotr Czerniak
Adrianna Antoszewska
Weronika Bargiel
Halszka Wajdowicz
Mateusz Warzocha
Aldona Sokołowska
author_facet Dominika Bąk
Julia Buszek
Piotr Czerniak
Adrianna Antoszewska
Weronika Bargiel
Halszka Wajdowicz
Mateusz Warzocha
Aldona Sokołowska
author_sort Dominika Bąk
collection DOAJ
description Introduction: Ketogenic and low-carbohydrate diets are characterized by a significant reduction in daily carbohydrate intake, resulting in ketone bodies becoming an alternative energy source to glucose. Studies over the past decade have confirmed the therapeutic potential of the ketogenic diet in such disease entities as diabetes, polycystic ovary syndrome, acne, cancer, neurological diseases. In recent years, there has been a marked increase in patients with obesity and diabetes mellitus type 2, which has increased the number of studies on the impact of a carbohydrate-restricted diet on the pathogenesis and therapeutic process in this disease. This paper comprehensively analyzes the pathogenesis of obesity, diabetes mellitus type 1 and 2, and the effect of carbohydrate-restricted diet on these disease. Aim of the Study: The purpose of this study is to examine the effects of low-carbohydrate and ketogenic diets on the pathogenesis and treatment of obesity, type 1  and 2 diabetes mellitus. Materials and Methods: An analysis of papers available in PubMed was performed. The following keywords were used : non-carbohydrate diet, ketogenic diet, obesity, diabeletes mellutis type 1, diabetes mellutis type 2 Basic results: The ketogenic diet has a proven effective effect in reducing body weight, and thus shows a preventive effect on the development of type 2 diabetes. Low-carbohydrate diets improve glucose control and lower HbA1c levels. In addition, such a dietary pattern can help reduce the dose of hypoglycemic medications. Conclusion: According to the recommendations, there is no single optimal nutritional model in patients with diabetes, while the use of low-carbohydrate and ketogenic diets can lead to the desired results and achieve therapeutic goals in patients with diabetes.
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spelling doaj-art-cf66b0aaf8254eb48e786796ab86277d2025-08-20T03:21:27ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062025-06-018210.12775/JEHS.2025.82.60329Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature ReviewDominika Bąk0https://orcid.org/0009-0008-0411-9064Julia Buszek1https://orcid.org/0009-0001-3832-2668Piotr Czerniak2https://orcid.org/0009-0007-3582-4586Adrianna Antoszewska3https://orcid.org/0009-0009-4518-1726Weronika Bargiel4https://orcid.org/0009-0008-5907-8159Halszka Wajdowicz5https://orcid.org/0009-0005-4454-8558Mateusz Warzocha6https://orcid.org/0009-0009-0683-3576Aldona Sokołowska7https://orcid.org/0009-0006-8723-2593University of Rzeszow, al. Rejtana 16c, 35-959 Rzeszów, PolandUniwersytet RzeszowskiUniwersytet RzeszowskiUniwersytet RzeszowskiUniwersytet RzeszowskiUniwersytet RzeszowskiUniwersytet RzeszowskiClinical Provincial Hospital No. 2 in Rzeszów, Poland Lwowska 60, 35-301 Rzeszów, Poland Introduction: Ketogenic and low-carbohydrate diets are characterized by a significant reduction in daily carbohydrate intake, resulting in ketone bodies becoming an alternative energy source to glucose. Studies over the past decade have confirmed the therapeutic potential of the ketogenic diet in such disease entities as diabetes, polycystic ovary syndrome, acne, cancer, neurological diseases. In recent years, there has been a marked increase in patients with obesity and diabetes mellitus type 2, which has increased the number of studies on the impact of a carbohydrate-restricted diet on the pathogenesis and therapeutic process in this disease. This paper comprehensively analyzes the pathogenesis of obesity, diabetes mellitus type 1 and 2, and the effect of carbohydrate-restricted diet on these disease. Aim of the Study: The purpose of this study is to examine the effects of low-carbohydrate and ketogenic diets on the pathogenesis and treatment of obesity, type 1  and 2 diabetes mellitus. Materials and Methods: An analysis of papers available in PubMed was performed. The following keywords were used : non-carbohydrate diet, ketogenic diet, obesity, diabeletes mellutis type 1, diabetes mellutis type 2 Basic results: The ketogenic diet has a proven effective effect in reducing body weight, and thus shows a preventive effect on the development of type 2 diabetes. Low-carbohydrate diets improve glucose control and lower HbA1c levels. In addition, such a dietary pattern can help reduce the dose of hypoglycemic medications. Conclusion: According to the recommendations, there is no single optimal nutritional model in patients with diabetes, while the use of low-carbohydrate and ketogenic diets can lead to the desired results and achieve therapeutic goals in patients with diabetes. https://apcz.umk.pl/JEHS/article/view/60329low-carbohydrate dietketogenic dietobesitydiabeletes mellutis type 1diabetes mellutis type 2
spellingShingle Dominika Bąk
Julia Buszek
Piotr Czerniak
Adrianna Antoszewska
Weronika Bargiel
Halszka Wajdowicz
Mateusz Warzocha
Aldona Sokołowska
Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review
Journal of Education, Health and Sport
low-carbohydrate diet
ketogenic diet
obesity
diabeletes mellutis type 1
diabetes mellutis type 2
title Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review
title_full Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review
title_fullStr Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review
title_full_unstemmed Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review
title_short Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review
title_sort role of ketogenic and low carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 a literature review
topic low-carbohydrate diet
ketogenic diet
obesity
diabeletes mellutis type 1
diabetes mellutis type 2
url https://apcz.umk.pl/JEHS/article/view/60329
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