Compatibility of the urodynamic findings and mixed urinary incontinence symptoms

Introduction: Mixed urinary incontinence (MUI) is one of the most common problems of middle-aged women besides pelvic organ prolapses (POPs), and associated urinary symptoms are common disorders among older women whose treatment is necessary for the improvement of quality of life. This study aimed t...

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Main Authors: Fatemeh Mallah, Parvin Bastani, Aila Kari, Ehsan Sepehran, Hanieh Salehi-Pourmehr
Format: Article
Language:English
Published: Tabriz University of Medical Sciences Press 2024-05-01
Series:Journal of Research in Clinical Medicine
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Online Access:https://jrcm.tbzmed.ac.ir/PDF/jrcm-12-11.pdf
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author Fatemeh Mallah
Parvin Bastani
Aila Kari
Ehsan Sepehran
Hanieh Salehi-Pourmehr
author_facet Fatemeh Mallah
Parvin Bastani
Aila Kari
Ehsan Sepehran
Hanieh Salehi-Pourmehr
author_sort Fatemeh Mallah
collection DOAJ
description Introduction: Mixed urinary incontinence (MUI) is one of the most common problems of middle-aged women besides pelvic organ prolapses (POPs), and associated urinary symptoms are common disorders among older women whose treatment is necessary for the improvement of quality of life. This study aimed to evaluate the agreement between the symptoms of patients with MUI and urodynamic findings. Methods: This analytic cross-sectional study was conducted on 170 MUI patients who underwent urodynamic evaluation for confirmation of the presumptive diagnosis. Findings comprise patients with "voiding phase symptoms", "detrusor overactivity" (DO), "bladder hypersensitivity", and "stress urinary incontinence" (SUI). The Kappa coefficient was used to evaluate the agreement between the symptoms and urodynamic findings. Sensitivity, specificity, and agreement of symptoms with corresponding urodynamic findings were determined. Univariate logistic regression was used to estimate the predictive value of clinical history compared to urodynamic findings. Results: According to the results, the mean (SD) age of women was 51.87 (11.20). The mean bladder capacity was 339.6 (134.24), and post-void residual was 35.46 (43.89) ml. We determined a sensitivity of 75%, a specificity of 78.3%, a positive predictive value (PPV) of 86.3%, and a 63.2% negative predictive value (NPV) for SUI symptoms. According to the chi-square test results and Cohen Kappa values, there was no agreement between the symptoms of patients with MUI and bladder hypersensitivity, DO, and SUI. The only agreement was observed between the urinary frequency and voiding phase symptoms (Cohen kappa: 0.124; P value=0.003). Conclusion: There was no agreement between urodynamic findings and MUI symptoms except for urinary frequency and voiding phase symptoms. Since no comprehensive study has been conducted on the correlation between the symptoms of patients with MUI and urodynamic findings in our setting, the necessity to conduct large clinical studies is recommended.
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spelling doaj-art-cf5d798d56e44df49162486ebead4a632025-08-20T01:58:04ZengTabriz University of Medical Sciences PressJournal of Research in Clinical Medicine2717-06162024-05-01121111110.34172/jrcm.33455jrcm-33455Compatibility of the urodynamic findings and mixed urinary incontinence symptomsFatemeh Mallah0Parvin Bastani1Aila Kari2Ehsan Sepehran3Hanieh Salehi-Pourmehr4Department of Gynecology, Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Gynecology, Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, IranDepartment of Gynecology, Women’s Reproductive Health Research Center, Tabriz University of Medical Sciences, Tabriz, IranUrology Department, Tabriz University of Medical Sciences, Tabriz, IranResearch Center for Evidence-Based Medicine, Iranian EBM Centre: A Joanna Briggs Institute (JBI) Center of Excellence, Tabriz University of Medical Sciences, Tabriz, IranIntroduction: Mixed urinary incontinence (MUI) is one of the most common problems of middle-aged women besides pelvic organ prolapses (POPs), and associated urinary symptoms are common disorders among older women whose treatment is necessary for the improvement of quality of life. This study aimed to evaluate the agreement between the symptoms of patients with MUI and urodynamic findings. Methods: This analytic cross-sectional study was conducted on 170 MUI patients who underwent urodynamic evaluation for confirmation of the presumptive diagnosis. Findings comprise patients with "voiding phase symptoms", "detrusor overactivity" (DO), "bladder hypersensitivity", and "stress urinary incontinence" (SUI). The Kappa coefficient was used to evaluate the agreement between the symptoms and urodynamic findings. Sensitivity, specificity, and agreement of symptoms with corresponding urodynamic findings were determined. Univariate logistic regression was used to estimate the predictive value of clinical history compared to urodynamic findings. Results: According to the results, the mean (SD) age of women was 51.87 (11.20). The mean bladder capacity was 339.6 (134.24), and post-void residual was 35.46 (43.89) ml. We determined a sensitivity of 75%, a specificity of 78.3%, a positive predictive value (PPV) of 86.3%, and a 63.2% negative predictive value (NPV) for SUI symptoms. According to the chi-square test results and Cohen Kappa values, there was no agreement between the symptoms of patients with MUI and bladder hypersensitivity, DO, and SUI. The only agreement was observed between the urinary frequency and voiding phase symptoms (Cohen kappa: 0.124; P value=0.003). Conclusion: There was no agreement between urodynamic findings and MUI symptoms except for urinary frequency and voiding phase symptoms. Since no comprehensive study has been conducted on the correlation between the symptoms of patients with MUI and urodynamic findings in our setting, the necessity to conduct large clinical studies is recommended.https://jrcm.tbzmed.ac.ir/PDF/jrcm-12-11.pdfurinary incontinenceurodynamicsbladder outlet obstructiondetrusor overactivitybladder hypersensitivity
spellingShingle Fatemeh Mallah
Parvin Bastani
Aila Kari
Ehsan Sepehran
Hanieh Salehi-Pourmehr
Compatibility of the urodynamic findings and mixed urinary incontinence symptoms
Journal of Research in Clinical Medicine
urinary incontinence
urodynamics
bladder outlet obstruction
detrusor overactivity
bladder hypersensitivity
title Compatibility of the urodynamic findings and mixed urinary incontinence symptoms
title_full Compatibility of the urodynamic findings and mixed urinary incontinence symptoms
title_fullStr Compatibility of the urodynamic findings and mixed urinary incontinence symptoms
title_full_unstemmed Compatibility of the urodynamic findings and mixed urinary incontinence symptoms
title_short Compatibility of the urodynamic findings and mixed urinary incontinence symptoms
title_sort compatibility of the urodynamic findings and mixed urinary incontinence symptoms
topic urinary incontinence
urodynamics
bladder outlet obstruction
detrusor overactivity
bladder hypersensitivity
url https://jrcm.tbzmed.ac.ir/PDF/jrcm-12-11.pdf
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AT ehsansepehran compatibilityoftheurodynamicfindingsandmixedurinaryincontinencesymptoms
AT haniehsalehipourmehr compatibilityoftheurodynamicfindingsandmixedurinaryincontinencesymptoms