Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine
Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel r...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2012/412412 |
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| _version_ | 1849683711462735872 |
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| author | Sarah Bajorek Roel Basaldua Katherine McGoogan Charla Miller Craig B. Sussman |
| author_facet | Sarah Bajorek Roel Basaldua Katherine McGoogan Charla Miller Craig B. Sussman |
| author_sort | Sarah Bajorek |
| collection | DOAJ |
| description | Gastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant’s unusual presentation, and details of the treatment regimen are discussed. |
| format | Article |
| id | doaj-art-cf5d0627e36d429383406fdd876f4855 |
| institution | DOAJ |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-cf5d0627e36d429383406fdd876f48552025-08-20T03:23:43ZengWileyCase Reports in Pediatrics2090-68032090-68112012-01-01201210.1155/2012/412412412412Neonatal Gastric Lactobezoar: Management with N-AcetylcysteineSarah Bajorek0Roel Basaldua1Katherine McGoogan2Charla Miller3Craig B. Sussman4Department of Pediatrics, University of Florida, Jacksonville, FL 32209, USADivision of Neonatology, Wolfson Children’s Hospital, Jacksonville, FL 32209, USADivision of Neonatology, Wolfson Children’s Hospital, Jacksonville, FL 32209, USADivision of Neonatology, Wolfson Children’s Hospital, Jacksonville, FL 32209, USADepartment of Pediatrics, University of Florida, Jacksonville, FL 32209, USAGastric lactobezoars (GLBs) are the most common form of bezoars in neonates and consist of aggregations of undigested milk constituents. GLB can present with a variety of intra-abdominal clinical symptoms, and occasionally, extra-abdominal symptoms. Conservative management, with a period of bowel rest and intravenous fluids, is the most common treatment regimen for uncomplicated GLB. Surgical measures are reserved for the rare complications of obstruction and/or perforation. Although limited, utilization of the protein-cleaving enzyme N-acetylcysteine has been described for the disintegration of GLB in toddlers. In this paper, we discuss the first documented use of N-acetylcysteine for a neonatal GLB. Supporting literature, the infant’s unusual presentation, and details of the treatment regimen are discussed.http://dx.doi.org/10.1155/2012/412412 |
| spellingShingle | Sarah Bajorek Roel Basaldua Katherine McGoogan Charla Miller Craig B. Sussman Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine Case Reports in Pediatrics |
| title | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
| title_full | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
| title_fullStr | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
| title_full_unstemmed | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
| title_short | Neonatal Gastric Lactobezoar: Management with N-Acetylcysteine |
| title_sort | neonatal gastric lactobezoar management with n acetylcysteine |
| url | http://dx.doi.org/10.1155/2012/412412 |
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