Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes
Carbapenemases have had increasing prevalence within the United States and worldwide. Here, we present a case of carbapenem-resistant Klebsiella pneumoniae (CRKP) which is unique due to the rarity of multiple mechanisms of resistance within the Klebsiella pneumoniae harboring New Delhi metallo-β-lac...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/crdi/8155592 |
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| author | Christopher Phan Kristen Tsai Christian M. Gill Robin Chamberland Christian Hendrix Rong Hou |
| author_facet | Christopher Phan Kristen Tsai Christian M. Gill Robin Chamberland Christian Hendrix Rong Hou |
| author_sort | Christopher Phan |
| collection | DOAJ |
| description | Carbapenemases have had increasing prevalence within the United States and worldwide. Here, we present a case of carbapenem-resistant Klebsiella pneumoniae (CRKP) which is unique due to the rarity of multiple mechanisms of resistance within the Klebsiella pneumoniae harboring New Delhi metallo-β-lactamases (NDM), oxacillinase-48 (OXA-48)-like, and cefotaximase (CTX-M) resistance genes, detected in a patient following an international travel. This case demonstrates the need for a multidisciplinary approach to optimize the treatment of multidrug-resistant Gram-negative organisms. |
| format | Article |
| id | doaj-art-cf58902169594617abd0ed4e955e20a6 |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-cf58902169594617abd0ed4e955e20a62025-02-08T00:00:06ZengWileyCase Reports in Infectious Diseases2090-66332025-01-01202510.1155/crdi/8155592Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical OutcomesChristopher Phan0Kristen Tsai1Christian M. Gill2Robin Chamberland3Christian Hendrix4Rong Hou5Department of Internal MedicineDepartment of Internal MedicineSSM Health Saint Louis University HospitalDepartment of PathologyDepartment of Internal MedicineDepartment of Internal MedicineCarbapenemases have had increasing prevalence within the United States and worldwide. Here, we present a case of carbapenem-resistant Klebsiella pneumoniae (CRKP) which is unique due to the rarity of multiple mechanisms of resistance within the Klebsiella pneumoniae harboring New Delhi metallo-β-lactamases (NDM), oxacillinase-48 (OXA-48)-like, and cefotaximase (CTX-M) resistance genes, detected in a patient following an international travel. This case demonstrates the need for a multidisciplinary approach to optimize the treatment of multidrug-resistant Gram-negative organisms.http://dx.doi.org/10.1155/crdi/8155592 |
| spellingShingle | Christopher Phan Kristen Tsai Christian M. Gill Robin Chamberland Christian Hendrix Rong Hou Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes Case Reports in Infectious Diseases |
| title | Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes |
| title_full | Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes |
| title_fullStr | Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes |
| title_full_unstemmed | Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes |
| title_short | Carbapenem-Resistant Klebsiella pneumoniae Isolated From a Patient in a Midwestern U.S. Hospital With a History of Indian Travel: Therapeutic Strategies and Clinical Outcomes |
| title_sort | carbapenem resistant klebsiella pneumoniae isolated from a patient in a midwestern u s hospital with a history of indian travel therapeutic strategies and clinical outcomes |
| url | http://dx.doi.org/10.1155/crdi/8155592 |
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