Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell Viability

The present work aimed to obtain and characterize sunflower seed oil (SO) enriched with compounds from turmeric rhizome (TR). For this purpose, the enriched oil was obtained from two strategies: extraction of the compounds from TR using SO as solvent (ESO) and simultaneous extraction of SO and TR co...

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Main Authors: Késia Corsato de Oliveira Segantini, Oscar de Oliveira Santos Junior, Vitor Augusto Dos Santos Garcia, Djéssica Tatiane Raspe, Camila da Silva
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Separations
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Online Access:https://www.mdpi.com/2297-8739/12/5/121
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author Késia Corsato de Oliveira Segantini
Oscar de Oliveira Santos Junior
Vitor Augusto Dos Santos Garcia
Djéssica Tatiane Raspe
Camila da Silva
author_facet Késia Corsato de Oliveira Segantini
Oscar de Oliveira Santos Junior
Vitor Augusto Dos Santos Garcia
Djéssica Tatiane Raspe
Camila da Silva
author_sort Késia Corsato de Oliveira Segantini
collection DOAJ
description The present work aimed to obtain and characterize sunflower seed oil (SO) enriched with compounds from turmeric rhizome (TR). For this purpose, the enriched oil was obtained from two strategies: extraction of the compounds from TR using SO as solvent (ESO) and simultaneous extraction of SO and TR compounds using ethyl acetate as solvent (ESOS). In these strategies, the effect of time (15 and 30 min) and temperature (60 and 70 °C) on the enrichment in relation to the curcuminoids content was determined. Evaluation of phytochemicals such as total phenolic compounds (TPCs), phenolic compound profile and fatty-acid profile and bioactivity by antioxidant potential (AP) was carriedoutin the enriched oils and in the SO;mean while, oxidative stability and cytotoxicity were evaluated using HaCaT (human immortalized keratinocyte) cells. From the results obtained, higher contents of curcuminoids (510 mg/100 g oil) were observed in the oil obtained from simultaneous extraction (ESOS) in a shorter time and lower temperature (15 min and 60 °C), and similar behavior was found for the content of phenolic compounds and antioxidant potential. The profile of phenolic compounds revealed the presence of phenolic acids, curcuminoids and terpenes in the composition of the enriched oils, which increased oxidative stability. The oils obtained did not show any cytotoxic effect against the cells tested, confirmed by the high survival rate (>88%) after 48 h of exposure.
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publishDate 2025-05-01
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spelling doaj-art-cf56ff45c4d44aaab36b8ee3e841032c2025-08-20T03:47:54ZengMDPI AGSeparations2297-87392025-05-0112512110.3390/separations12050121Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell ViabilityKésia Corsato de Oliveira Segantini0Oscar de Oliveira Santos Junior1Vitor Augusto Dos Santos Garcia2Djéssica Tatiane Raspe3Camila da Silva4Programa de Pós-GraduaçãoemSustentabilidade, UniversidadeEstadual de Maringá, Av. Angelo Moreira da Fonseca, 1800, Umuarama 87506-370, PR, BrazilLaboratório de Química de Alimentos, Programa de Pós-GraduaçãoemQuímica, UniversidadeEstadual de Maringá (UEM), Av. Colombo, 5790, Maringá 87020-900, PR, BrazilFaculdade de CiênciasAgronômicas, UniversidadeEstadualPaulista“Júlio de MesquitaFilho”, Botucatu 18618687, SP, BrazilPrograma de Pós-GraduaçãoemEngenhariaQuímica, UniversidadeEstadual de Maringá, Av. Colombo, 5790, Maringá 87020-900, PR, BrazilPrograma de Pós-GraduaçãoemSustentabilidade, UniversidadeEstadual de Maringá, Av. Angelo Moreira da Fonseca, 1800, Umuarama 87506-370, PR, BrazilThe present work aimed to obtain and characterize sunflower seed oil (SO) enriched with compounds from turmeric rhizome (TR). For this purpose, the enriched oil was obtained from two strategies: extraction of the compounds from TR using SO as solvent (ESO) and simultaneous extraction of SO and TR compounds using ethyl acetate as solvent (ESOS). In these strategies, the effect of time (15 and 30 min) and temperature (60 and 70 °C) on the enrichment in relation to the curcuminoids content was determined. Evaluation of phytochemicals such as total phenolic compounds (TPCs), phenolic compound profile and fatty-acid profile and bioactivity by antioxidant potential (AP) was carriedoutin the enriched oils and in the SO;mean while, oxidative stability and cytotoxicity were evaluated using HaCaT (human immortalized keratinocyte) cells. From the results obtained, higher contents of curcuminoids (510 mg/100 g oil) were observed in the oil obtained from simultaneous extraction (ESOS) in a shorter time and lower temperature (15 min and 60 °C), and similar behavior was found for the content of phenolic compounds and antioxidant potential. The profile of phenolic compounds revealed the presence of phenolic acids, curcuminoids and terpenes in the composition of the enriched oils, which increased oxidative stability. The oils obtained did not show any cytotoxic effect against the cells tested, confirmed by the high survival rate (>88%) after 48 h of exposure.https://www.mdpi.com/2297-8739/12/5/121<i>Curcuma longa</i> L.curcuminoidsantioxidant potentialphytochemical<i>Helianthus annuus</i> L.
spellingShingle Késia Corsato de Oliveira Segantini
Oscar de Oliveira Santos Junior
Vitor Augusto Dos Santos Garcia
Djéssica Tatiane Raspe
Camila da Silva
Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell Viability
Separations
<i>Curcuma longa</i> L.
curcuminoids
antioxidant potential
phytochemical
<i>Helianthus annuus</i> L.
title Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell Viability
title_full Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell Viability
title_fullStr Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell Viability
title_full_unstemmed Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell Viability
title_short Sunflower Seed Oil Enriched with Compounds from the Turmeric Rhizome: Extraction, Characterization and Cell Viability
title_sort sunflower seed oil enriched with compounds from the turmeric rhizome extraction characterization and cell viability
topic <i>Curcuma longa</i> L.
curcuminoids
antioxidant potential
phytochemical
<i>Helianthus annuus</i> L.
url https://www.mdpi.com/2297-8739/12/5/121
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