ATTR Epidemiology, Genetics, and Prognostic Factors

ATTR Epidemiology, Genetics, and Prognostic Factors

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed disease and an underestimated cause of both heart failure and conduction abnormalities. It is characterized by pathologic accumulation of extracellular protein arising from unstable transthyretin (TTR) tetramers, which dissociate in...

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Bibliographic Details
Main Authors: Chukwuemeka A. Obi, William C. Mostertz, Jan M. Griffin, Daniel P. Judge
Format: Article
Language:English
Published: Houston Methodist DeBakey Heart & Vascular Center 2022-03-01
Series:Methodist DeBakey Cardiovascular Journal
Subjects:
transthyretin
misfolding
attr amyloidosis
mutation
prognosis
Online Access:https://account.journal.houstonmethodist.org/index.php/up-j-mdbcj/article/view/1066
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