Physical activity and mortality in the general population with and without major depression
Background and aims: It is not yet well understood whether physical activity (PA) may protect against elevated mortality in major depression. Answering this question has implications for policy and practice. The aim of this study was to estimate the association of PA with mortality in maj...
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Academia.edu Journals
2024-09-01
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| Series: | Academia Mental Health & Well-Being |
| Online Access: | https://www.academia.edu/123843731/Does_physical_activity_protect_against_all_cause_mortality_in_major_depressive_disorder |
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| author | Vagner Deuel de O. Tavares Jeanne V. A. Williams Vandad Sharifi Andrew Bulloch Gina Dimitropoulos Nicole Leite Galvão-Coelho Scott Patten |
| author_facet | Vagner Deuel de O. Tavares Jeanne V. A. Williams Vandad Sharifi Andrew Bulloch Gina Dimitropoulos Nicole Leite Galvão-Coelho Scott Patten |
| author_sort | Vagner Deuel de O. Tavares |
| collection | DOAJ |
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Background and aims: It is not yet well understood whether physical activity (PA) may protect against elevated mortality in major depression. Answering this question has implications for policy and practice. The aim of this study was to estimate the association of PA with mortality in major depressive disorder (MDD). Methods: We used data from the Canadian Community Health Survey—Mental Health and Well-Being (CCHS 2002), conducted in 2002 (n = 31,200), and the Canadian Community Health Survey—Mental Health (CCHS-MH 2012), conducted in 2012 (n = 20,935), for this analysis. Recreational PA was measured using metabolic equivalent of task (MET) values, classifying participants as active, moderately active, and physically inactive in the 2002 survey and as very active, active, moderately active, and physically inactive in the 2012 survey. Major depression was assessed using a fully structured diagnostic instrument, the Composite International Diagnostic Interview. Mortality data was obtained through data linkage. The analysis used Cox proportional hazard models to explore the associations. Results: PA in the 2002 survey was protective: HR 0.69 (95% CI 0.64–0.74) and HR 0.77 (95% CI 0.72–0.83) for the active and moderately active groups, respectively. In the 2012 survey, the HRs were 0.55 (95% CI 0.43–0.70), 0.57 (95% CI 0.43–0.75), and 0.59 (95% CI 0.46–0.76) for the very active, active, and moderately active groups, respectively. No interactions were significant. Conclusions: These results indicate that PA protects against elevated mortality to the same extent in those with MDD as in those without. These findings, which arise from a representative sample, support continued efforts to integrate PA into the management of depressive disorders at the population level. |
| format | Article |
| id | doaj-art-cf4845085d0f4856b2a4d54347bf80c3 |
| institution | DOAJ |
| issn | 2997-9196 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Academia.edu Journals |
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| series | Academia Mental Health & Well-Being |
| spelling | doaj-art-cf4845085d0f4856b2a4d54347bf80c32025-08-20T03:12:20ZengAcademia.edu JournalsAcademia Mental Health & Well-Being2997-91962024-09-011210.20935/MHealthWellB7335Physical activity and mortality in the general population with and without major depressionVagner Deuel de O. Tavares0Jeanne V. A. Williams1Vandad Sharifi2Andrew Bulloch3Gina Dimitropoulos4Nicole Leite Galvão-Coelho5Scott Patten6Laboratory of Hormone Measurement, Department of Physiology, Biosciences Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte 59078-970, Brazil.Mathison Centre for Mental Health Research & Education, Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB T2N-4Z6, Canada.Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Tehran Province 13337-95914, Iran.Mathison Centre for Mental Health Research & Education, Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB T2N-4Z6, Canada.Mathison Centre for Mental Health Research & Education, Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB T2N-4Z6, Canada.Laboratory of Hormone Measurement, Department of Physiology, Biosciences Center, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte 59078-970, Brazil.Mathison Centre for Mental Health Research & Education, Department of Psychiatry, Cumming School of Medicine, University of Calgary, Calgary, AB T2N-4Z6, Canada. Background and aims: It is not yet well understood whether physical activity (PA) may protect against elevated mortality in major depression. Answering this question has implications for policy and practice. The aim of this study was to estimate the association of PA with mortality in major depressive disorder (MDD). Methods: We used data from the Canadian Community Health Survey—Mental Health and Well-Being (CCHS 2002), conducted in 2002 (n = 31,200), and the Canadian Community Health Survey—Mental Health (CCHS-MH 2012), conducted in 2012 (n = 20,935), for this analysis. Recreational PA was measured using metabolic equivalent of task (MET) values, classifying participants as active, moderately active, and physically inactive in the 2002 survey and as very active, active, moderately active, and physically inactive in the 2012 survey. Major depression was assessed using a fully structured diagnostic instrument, the Composite International Diagnostic Interview. Mortality data was obtained through data linkage. The analysis used Cox proportional hazard models to explore the associations. Results: PA in the 2002 survey was protective: HR 0.69 (95% CI 0.64–0.74) and HR 0.77 (95% CI 0.72–0.83) for the active and moderately active groups, respectively. In the 2012 survey, the HRs were 0.55 (95% CI 0.43–0.70), 0.57 (95% CI 0.43–0.75), and 0.59 (95% CI 0.46–0.76) for the very active, active, and moderately active groups, respectively. No interactions were significant. Conclusions: These results indicate that PA protects against elevated mortality to the same extent in those with MDD as in those without. These findings, which arise from a representative sample, support continued efforts to integrate PA into the management of depressive disorders at the population level.https://www.academia.edu/123843731/Does_physical_activity_protect_against_all_cause_mortality_in_major_depressive_disorder |
| spellingShingle | Vagner Deuel de O. Tavares Jeanne V. A. Williams Vandad Sharifi Andrew Bulloch Gina Dimitropoulos Nicole Leite Galvão-Coelho Scott Patten Physical activity and mortality in the general population with and without major depression Academia Mental Health & Well-Being |
| title | Physical activity and mortality in the general population with and without major depression |
| title_full | Physical activity and mortality in the general population with and without major depression |
| title_fullStr | Physical activity and mortality in the general population with and without major depression |
| title_full_unstemmed | Physical activity and mortality in the general population with and without major depression |
| title_short | Physical activity and mortality in the general population with and without major depression |
| title_sort | physical activity and mortality in the general population with and without major depression |
| url | https://www.academia.edu/123843731/Does_physical_activity_protect_against_all_cause_mortality_in_major_depressive_disorder |
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