CLOCK Genes and Circadian Rhythmicity in Alzheimer Disease
Disturbed circadian rhythms with sleep problems and disrupted diurnal activity are often seen in patients suffering from Alzheimer disease (AD). Both endogenous CLOCK genes and external Zeitgeber are responsible for the maintenance of circadian rhythmicity in humans. Therefore, modifications of the...
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Main Authors: | J. Thome, A. N. Coogan, A. G. Woods, C. C. Darie, F. Häßler |
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Format: | Article |
Language: | English |
Published: |
Wiley
2011-01-01
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Series: | Journal of Aging Research |
Online Access: | http://dx.doi.org/10.4061/2011/383091 |
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