Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis

Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis

Abstract Acute kidney injury (AKI) is a common and life-threatening condition associated with cell death, where ferroptosis plays a critical role. Chemerin, primarily produced in white adipose tissue, has multiple biological functions in renal pathophysiology. However, to date, whether and how cheme...

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Bibliographic Details
Main Authors: Yidan Ma, Shengnan Fei, Xu Chen, Yuanyuan Gui, Bing Zhou, Tianya Xiang, Jianhang Liu, Kun Yue, Qingxin Li, Wei Jiang, Cheng Sun, Xinzhong Huang
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07377-x
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