Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte Count
Objective: To evaluate the diagnostic utility of ultrasound (US) in the diagnosis of acute appendicitis in correlation with total leukocyte count (TLC). Materials and Methods: This cross sectional comparative study was conducted at the Radiology and Pathology Departments of CMH Lahore from 1st Febr...
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| Format: | Article |
| Language: | English |
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Bahria Univerisy Health Sciences, Campus Karachi
2015-06-01
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| Series: | Journal of Bahria University Medical and Dental College |
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| Online Access: | https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/116 |
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| author | Muhammad Adeel Azhar Atif Latif Mashkoor Ahmad Faisal Mahmood |
| author_facet | Muhammad Adeel Azhar Atif Latif Mashkoor Ahmad Faisal Mahmood |
| author_sort | Muhammad Adeel Azhar |
| collection | DOAJ |
| description |
Objective: To evaluate the diagnostic utility of ultrasound (US) in the diagnosis of acute appendicitis in correlation with total
leukocyte count (TLC).
Materials and Methods: This cross sectional comparative study was conducted at the Radiology and Pathology Departments
of CMH Lahore from 1st February 2007 to 31st January 2008. A total of 125 suspectedpatientsof appendicitis were included in
the study through non-probability purposive sampling. They all underwent US evaluation and laboratory assessment (TLC).
Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of US findings and TLC were
calculated keeping surgical findings and histopathology of the removed appendix as gold standard whenever appendecectomy
was carried out.
Results:Among 62 patients finally proven to be suffering from acute appendicitis US correctly diagnosed the same in 55 (89%),
whereas a normal appendix was visualized in 30 (48%) out of the remaining 63 non – appendicitis patients. The most accurate
appendiceal finding for appendicitis was adiameter of 6 mm or larger, with a sensitivity of 96%, specificity of 97%,NPV of
98%, and PPV of 98%.The lack of visualization of the appendixwith US had a NPV of 82%. An increase in TLC had a PPV
of 66%, whereas normal TLC had a NPV of 73% whereas those of US were 96% and 90% respectively. By utilizing US as an
adjunct to clinical evaluation, negative appendectomy rate was lessened to 3.2%.
Conclusion: US have better diagnostic utility than TLC in the diagnosis of acute appendicitis.
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| format | Article |
| id | doaj-art-cf2af248ee984a378347b2b190527d91 |
| institution | DOAJ |
| issn | 2220-7562 2617-9482 |
| language | English |
| publishDate | 2015-06-01 |
| publisher | Bahria Univerisy Health Sciences, Campus Karachi |
| record_format | Article |
| series | Journal of Bahria University Medical and Dental College |
| spelling | doaj-art-cf2af248ee984a378347b2b190527d912025-08-20T02:45:07ZengBahria Univerisy Health Sciences, Campus KarachiJournal of Bahria University Medical and Dental College2220-75622617-94822015-06-0152Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte CountMuhammad Adeel AzharAtif LatifMashkoor AhmadFaisal Mahmood Objective: To evaluate the diagnostic utility of ultrasound (US) in the diagnosis of acute appendicitis in correlation with total leukocyte count (TLC). Materials and Methods: This cross sectional comparative study was conducted at the Radiology and Pathology Departments of CMH Lahore from 1st February 2007 to 31st January 2008. A total of 125 suspectedpatientsof appendicitis were included in the study through non-probability purposive sampling. They all underwent US evaluation and laboratory assessment (TLC). Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of US findings and TLC were calculated keeping surgical findings and histopathology of the removed appendix as gold standard whenever appendecectomy was carried out. Results:Among 62 patients finally proven to be suffering from acute appendicitis US correctly diagnosed the same in 55 (89%), whereas a normal appendix was visualized in 30 (48%) out of the remaining 63 non – appendicitis patients. The most accurate appendiceal finding for appendicitis was adiameter of 6 mm or larger, with a sensitivity of 96%, specificity of 97%,NPV of 98%, and PPV of 98%.The lack of visualization of the appendixwith US had a NPV of 82%. An increase in TLC had a PPV of 66%, whereas normal TLC had a NPV of 73% whereas those of US were 96% and 90% respectively. By utilizing US as an adjunct to clinical evaluation, negative appendectomy rate was lessened to 3.2%. Conclusion: US have better diagnostic utility than TLC in the diagnosis of acute appendicitis. https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/116Ultrasonography, Appendix. Appendicitis, Appendicectomy |
| spellingShingle | Muhammad Adeel Azhar Atif Latif Mashkoor Ahmad Faisal Mahmood Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte Count Journal of Bahria University Medical and Dental College Ultrasonography, Appendix. Appendicitis, Appendicectomy |
| title | Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte Count |
| title_full | Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte Count |
| title_fullStr | Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte Count |
| title_full_unstemmed | Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte Count |
| title_short | Diagnostic Utility of Ultrasound in Acute Appendicitis in Correlation with Total Leukocyte Count |
| title_sort | diagnostic utility of ultrasound in acute appendicitis in correlation with total leukocyte count |
| topic | Ultrasonography, Appendix. Appendicitis, Appendicectomy |
| url | https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/116 |
| work_keys_str_mv | AT muhammadadeelazhar diagnosticutilityofultrasoundinacuteappendicitisincorrelationwithtotalleukocytecount AT atiflatif diagnosticutilityofultrasoundinacuteappendicitisincorrelationwithtotalleukocytecount AT mashkoorahmad diagnosticutilityofultrasoundinacuteappendicitisincorrelationwithtotalleukocytecount AT faisalmahmood diagnosticutilityofultrasoundinacuteappendicitisincorrelationwithtotalleukocytecount |