The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategies
Acne vulgaris, which is one of the most common inflammatory skin diseases, affects millions of people worldwide. It is most common during adolescence, but also occurs in adults. Its pathogenesis is the result of a complex interaction of genetic, hormonal, environmental and psychosocial factors. Tra...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-04-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/59769 |
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| _version_ | 1849698563649437696 |
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| author | Maria Madejska Aleksandra Rudzka Antonina Drzewiecka Artur Drzewiecki Wiktor Korczak Monika Gaszyńska Wojciech Falkowski Anna Krysińska Weronika Woźniak Jakub Magielski |
| author_facet | Maria Madejska Aleksandra Rudzka Antonina Drzewiecka Artur Drzewiecki Wiktor Korczak Monika Gaszyńska Wojciech Falkowski Anna Krysińska Weronika Woźniak Jakub Magielski |
| author_sort | Maria Madejska |
| collection | DOAJ |
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Acne vulgaris, which is one of the most common inflammatory skin diseases, affects millions of people worldwide. It is most common during adolescence, but also occurs in adults. Its pathogenesis is the result of a complex interaction of genetic, hormonal, environmental and psychosocial factors. Traditional models have focused on excessive sebum production, impaired keratinisation and colonisation by Cutibacterium acnes. Recent studies show that, in addition to hormonal, genetic and environmental factors, psychological stress is recognised as an important factor influencing the pathogenesis and exacerbation of acne. This review examines the mechanisms by which stress influences the development and severity of acne (considering the role of the skin microbiome, diet and lifestyle), presenting current scientific reports from recent years, and discusses modern therapeutic strategies combining standard pharmacotherapy with mental health support interventions, dietary modification and probiotic therapy.
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| format | Article |
| id | doaj-art-cf240954eb254c8396cb46e2ae7d7a19 |
| institution | DOAJ |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-cf240954eb254c8396cb46e2ae7d7a192025-08-20T03:18:52ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-04-014010.12775/QS.2025.40.59769The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategiesMaria Madejska0https://orcid.org/0009-0004-2570-2313Aleksandra Rudzka1https://orcid.org/0009-0008-6602-5522Antonina Drzewiecka2https://orcid.org/0009-0007-1007-2082Artur Drzewiecki3https://orcid.org/0009-0008-1664-1087Wiktor Korczak4https://orcid.org/0009-0004-2177-7027Monika Gaszyńska5https://orcid.org/0009-0007-0784-1370Wojciech Falkowski6https://orcid.org/0009-0004-7831-2570Anna Krysińska7https://orcid.org/0009-0001-8633-8410Weronika Woźniak8https://orcid.org/0009-0007-4920-4230Jakub Magielski9https://orcid.org/0009-0003-0737-6262Masovian Specialist Hospital in Radom, ul. Juliana Aleksandrowicza 5, 26-617 Radom, PLMasovian Specialist Hospital in Radom, ul. Juliana Aleksandrowicza 5, 26-617 Radom, PLJan Biziel University Hospital No. 2 in Bydgoszcz: Bydgoszcz, Kujawsko-Pomorskie, PLUniversity Hospital A. Jurasz No.1: Bydgoszcz, Kujawsko-Pomorskie, PLProvincial Specialist Hospital in Włocławek, ul. Wieniecka 49, 87–800 Włocławek; PLProvincial Hospital in Bielsko-Biała , Al.Armii Krajowej 101, 43-316 Bielsko-Biała, PLProvincial Hospital in Bielsko-Biała , Al.Armii Krajowej 101, 43-316 Bielsko-Biała, PLDr. Emil Warmiński Clinical Hospital of the Bydgoszcz University of Technology: Bydgoszcz, PLIndependent Public Health Care Facility in Słupca, ul. Traugutta 7 62-400 Słupca, PLIndependent Public Multi-Specialist Health Care Facility of the Ministry of Internal Affairs and Administration in Bydgoszcz; Bydgoszcz, Kujawsko-pomorskie, PL Acne vulgaris, which is one of the most common inflammatory skin diseases, affects millions of people worldwide. It is most common during adolescence, but also occurs in adults. Its pathogenesis is the result of a complex interaction of genetic, hormonal, environmental and psychosocial factors. Traditional models have focused on excessive sebum production, impaired keratinisation and colonisation by Cutibacterium acnes. Recent studies show that, in addition to hormonal, genetic and environmental factors, psychological stress is recognised as an important factor influencing the pathogenesis and exacerbation of acne. This review examines the mechanisms by which stress influences the development and severity of acne (considering the role of the skin microbiome, diet and lifestyle), presenting current scientific reports from recent years, and discusses modern therapeutic strategies combining standard pharmacotherapy with mental health support interventions, dietary modification and probiotic therapy. https://apcz.umk.pl/QS/article/view/59769acnestressHPA axisoxidative stressmicrobiomeskin barrier |
| spellingShingle | Maria Madejska Aleksandra Rudzka Antonina Drzewiecka Artur Drzewiecki Wiktor Korczak Monika Gaszyńska Wojciech Falkowski Anna Krysińska Weronika Woźniak Jakub Magielski The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategies Quality in Sport acne stress HPA axis oxidative stress microbiome skin barrier |
| title | The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategies |
| title_full | The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategies |
| title_fullStr | The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategies |
| title_full_unstemmed | The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategies |
| title_short | The influence of stress and other behavioural factors on the onset and exacerbation of acne - a review of pathogenetic mechanisms, interactions between body systems and directions for therapeutic strategies |
| title_sort | influence of stress and other behavioural factors on the onset and exacerbation of acne a review of pathogenetic mechanisms interactions between body systems and directions for therapeutic strategies |
| topic | acne stress HPA axis oxidative stress microbiome skin barrier |
| url | https://apcz.umk.pl/QS/article/view/59769 |
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