IP3R2-Mediated Astrocytic Ca<sup>2+</sup> Transients Are Critical to Sustain Modulatory Effects of Locomotion on Neurons in Mouse Somatosensory Cortex

Accumulating studies have shown that astrocytes are essential for regulating neurons at both synaptic and circuit levels. The main mechanism of brain astrocytic intracellular Ca<sup>2+</sup> activity is through the release of Ca<sup>2+</sup> via the inositol 1,4,5-trisphospha...

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Bibliographic Details
Main Authors: Mario Fernández de la Puebla, Xiaoyi Zhang, Erlend A. Nagelhus, Magnar Bjørås, Wannan Tang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/14/14/1103
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