Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study
ObjectiveTo evaluate remote participant engagement in a clinical study over time, based on data from the Project Baseline Health Study (PBHS), a hybrid in-person and virtual study.MethodsThe PBHS enrolled 2,502 adult US residents from March 3, 2017 to April 26, 2019, with a ≤5-year follow-up. We sum...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
|
| Series: | Frontiers in Digital Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fdgth.2025.1520132/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849683699641090048 |
|---|---|
| author | Megan K. Carroll Safa Faheem Jean Bouteiller Adrian Hernandez Kenneth W. Mahaffey Jessica L. Mega Neha Pagidipati Terry Schaack Svati H. Shah Sumana Shashidhar Susan Swope Donna Williams R. Scooter Plowman Edgar P. Simard Sarah A. Short Shannon S. Sullivan Shannon S. Sullivan |
| author_facet | Megan K. Carroll Safa Faheem Jean Bouteiller Adrian Hernandez Kenneth W. Mahaffey Jessica L. Mega Neha Pagidipati Terry Schaack Svati H. Shah Sumana Shashidhar Susan Swope Donna Williams R. Scooter Plowman Edgar P. Simard Sarah A. Short Shannon S. Sullivan Shannon S. Sullivan |
| author_sort | Megan K. Carroll |
| collection | DOAJ |
| description | ObjectiveTo evaluate remote participant engagement in a clinical study over time, based on data from the Project Baseline Health Study (PBHS), a hybrid in-person and virtual study.MethodsThe PBHS enrolled 2,502 adult US residents from March 3, 2017 to April 26, 2019, with a ≤5-year follow-up. We summarized 4-year retention and rates of longitudinal patient-reported outcome survey completion. We investigated participant characteristics for their associations with quarterly remote survey completion using regression models.ResultsOf the total participants (N = 2,502), 94% remained enrolled after 4 years and 60% completed all annual visits; 2,490 participants stayed enrolled for at least one quarter. The median (IQR) number of remote electronic survey sets completed was 8 (3–12), of a possible 16. Age [odds ratio (OR), >70 vs. ≤30 years: 2.56; 95% CI: 2.24–2.94] and education (OR, advanced degree vs. ≤high school: 1.36; 95% CI: 1.22–1.52) were positively associated with remote survey completion. Participants with lower odds of completion were Black (OR vs. White: 0.73; 95% CI: 0.67–0.80), Hispanic (OR vs. non-Hispanic: 0.84; 95% CI: 0.77–0.93), or had at least mild symptoms of depression (OR vs. without: 0.90; 95% CI: 0.84–0.96) or anxiety (OR vs. without: 0.84; 95% CI: 0.78–0.90).ConclusionsOverall, 94% of PBHS participants remained enrolled after four years. Age, race, ethnicity, income, education, and symptomatic depression/anxiety were significantly associated with longitudinal remote questionnaire completion. These findings on engagement over time may inform future longitudinal study design.Clinical Trial RegistrationClinicaltrials.gov, identifier (NCT03154346). |
| format | Article |
| id | doaj-art-cf14c347b076402a9e66e8decaee6be7 |
| institution | DOAJ |
| issn | 2673-253X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Digital Health |
| spelling | doaj-art-cf14c347b076402a9e66e8decaee6be72025-08-20T03:23:43ZengFrontiers Media S.A.Frontiers in Digital Health2673-253X2025-06-01710.3389/fdgth.2025.15201321520132Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health studyMegan K. Carroll0Safa Faheem1Jean Bouteiller2Adrian Hernandez3Kenneth W. Mahaffey4Jessica L. Mega5Neha Pagidipati6Terry Schaack7Svati H. Shah8Sumana Shashidhar9Susan Swope10Donna Williams11R. Scooter Plowman12Edgar P. Simard13Sarah A. Short14Shannon S. Sullivan15Shannon S. Sullivan16Verily Life Sciences, South San Francisco, CA, United StatesVerily Life Sciences, South San Francisco, CA, United StatesVerily Life Sciences, South San Francisco, CA, United StatesDuke University, Durham, NC, United StatesStanford Department of Medicine, Stanford University School of Medicine, Stanford, CA, United StatesVerily Life Sciences, South San Francisco, CA, United StatesDuke University, Durham, NC, United StatesCalifornia Health & Longevity Institute, Westlake Village, CA, United StatesDuke University, Durham, NC, United StatesStanford Department of Medicine, Stanford University School of Medicine, Stanford, CA, United StatesStanford Department of Medicine, Stanford University School of Medicine, Stanford, CA, United StatesStanford Department of Medicine, Stanford University School of Medicine, Stanford, CA, United StatesVerily Life Sciences, South San Francisco, CA, United StatesVerily Life Sciences, South San Francisco, CA, United StatesVerily Life Sciences, South San Francisco, CA, United StatesVerily Life Sciences, South San Francisco, CA, United StatesDepartment of Pediatrics, Division of Pulmonary, Asthma and Sleep Medicine, Stanford University School of Medicine, Stanford, CA, United StatesObjectiveTo evaluate remote participant engagement in a clinical study over time, based on data from the Project Baseline Health Study (PBHS), a hybrid in-person and virtual study.MethodsThe PBHS enrolled 2,502 adult US residents from March 3, 2017 to April 26, 2019, with a ≤5-year follow-up. We summarized 4-year retention and rates of longitudinal patient-reported outcome survey completion. We investigated participant characteristics for their associations with quarterly remote survey completion using regression models.ResultsOf the total participants (N = 2,502), 94% remained enrolled after 4 years and 60% completed all annual visits; 2,490 participants stayed enrolled for at least one quarter. The median (IQR) number of remote electronic survey sets completed was 8 (3–12), of a possible 16. Age [odds ratio (OR), >70 vs. ≤30 years: 2.56; 95% CI: 2.24–2.94] and education (OR, advanced degree vs. ≤high school: 1.36; 95% CI: 1.22–1.52) were positively associated with remote survey completion. Participants with lower odds of completion were Black (OR vs. White: 0.73; 95% CI: 0.67–0.80), Hispanic (OR vs. non-Hispanic: 0.84; 95% CI: 0.77–0.93), or had at least mild symptoms of depression (OR vs. without: 0.90; 95% CI: 0.84–0.96) or anxiety (OR vs. without: 0.84; 95% CI: 0.78–0.90).ConclusionsOverall, 94% of PBHS participants remained enrolled after four years. Age, race, ethnicity, income, education, and symptomatic depression/anxiety were significantly associated with longitudinal remote questionnaire completion. These findings on engagement over time may inform future longitudinal study design.Clinical Trial RegistrationClinicaltrials.gov, identifier (NCT03154346).https://www.frontiersin.org/articles/10.3389/fdgth.2025.1520132/fullresearch participant engagementparticipant retentionremote studycohort studypatient-reported outcomessocial determinants of health |
| spellingShingle | Megan K. Carroll Safa Faheem Jean Bouteiller Adrian Hernandez Kenneth W. Mahaffey Jessica L. Mega Neha Pagidipati Terry Schaack Svati H. Shah Sumana Shashidhar Susan Swope Donna Williams R. Scooter Plowman Edgar P. Simard Sarah A. Short Shannon S. Sullivan Shannon S. Sullivan Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study Frontiers in Digital Health research participant engagement participant retention remote study cohort study patient-reported outcomes social determinants of health |
| title | Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study |
| title_full | Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study |
| title_fullStr | Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study |
| title_full_unstemmed | Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study |
| title_short | Retention and characteristics associated with remote questionnaire completion in a general population cohort study: the project baseline health study |
| title_sort | retention and characteristics associated with remote questionnaire completion in a general population cohort study the project baseline health study |
| topic | research participant engagement participant retention remote study cohort study patient-reported outcomes social determinants of health |
| url | https://www.frontiersin.org/articles/10.3389/fdgth.2025.1520132/full |
| work_keys_str_mv | AT megankcarroll retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT safafaheem retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT jeanbouteiller retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT adrianhernandez retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT kennethwmahaffey retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT jessicalmega retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT nehapagidipati retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT terryschaack retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT svatihshah retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT sumanashashidhar retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT susanswope retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT donnawilliams retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT rscooterplowman retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT edgarpsimard retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT sarahashort retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT shannonssullivan retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy AT shannonssullivan retentionandcharacteristicsassociatedwithremotequestionnairecompletioninageneralpopulationcohortstudytheprojectbaselinehealthstudy |