Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI)
Objective: The validation study of the Thai version of the M.D. Anderson Dysphagia Inventory (TH-MDADI) addresses a critical gap in head and neck cancer (HNC) care in Thailand. At leading institutions like Siriraj Hospital, patient-reported outcomes have been historically neglected, with care prima...
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Faculty of Medicine Siriraj Hospital
2025-04-01
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| Series: | Siriraj Medical Journal |
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| Online Access: | https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/272679 |
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| author | Warut Pongsapich Narin Ratanaprasert Prachya Maneeprasopchoke Paveena Pithuksurachai Cheerasook Chongkolwatana Chanticha Chotigavanich Paiboon Sureepong Sunun Ongard Phawin Keskool |
| author_facet | Warut Pongsapich Narin Ratanaprasert Prachya Maneeprasopchoke Paveena Pithuksurachai Cheerasook Chongkolwatana Chanticha Chotigavanich Paiboon Sureepong Sunun Ongard Phawin Keskool |
| author_sort | Warut Pongsapich |
| collection | DOAJ |
| description |
Objective: The validation study of the Thai version of the M.D. Anderson Dysphagia Inventory (TH-MDADI) addresses a critical gap in head and neck cancer (HNC) care in Thailand. At leading institutions like Siriraj Hospital, patient-reported outcomes have been historically neglected, with care primarily focusing on routine medical services. This study aimed to validate the TH-MDADI to enhance dysphagia assessment and promote patient centered care.
Materials and Methods: In this longitudinal prospective study, 66 HNC patients completed the TH-MDADI and SF-36 at baseline, pre-treatment, and post-treatment at Siriraj Hospital. Psychometric properties were evaluated, including internal consistency (Cronbach’s α), test-retest reliability (intraclass correlation coefficient, ICC), convergent and discriminant validity (correlations with SF-36 domains), and responsiveness (standardized response mean, SRM).
Results: The TH-MDADI demonstrated excellent internal consistency (Cronbach’s α = 0.93) and test-retest reliability (ICC = 0.92, 95% CI: 0.88–0.96). Strong correlations with related SF-36 domains (r = 0.64-0.74, p < 0.001) established convergent validity, while weak correlations with unrelated domains confirmed discriminant validity. High responsiveness to change post-treatment was observed, particularly in the Global (SRM = 3.83) and Emotional (SRM = 3.17) subscales.
Conclusion: The TH-MDADI demonstrates robust psychometric properties, establishing its value as a reliable tool for assessing dysphagia-related quality of life in Thai HNC patients. This validation represents a significant advancement in Thai cancer care, addressing the historical neglect of patient-reported outcomes. By providing clinicians with a validated assessment instrument, this study promotes a more systematic, patient-centered approach to HNC treatment in Thailand.
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| format | Article |
| id | doaj-art-cf09ba512c6e45e481316babef002cea |
| institution | DOAJ |
| issn | 2228-8082 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Faculty of Medicine Siriraj Hospital |
| record_format | Article |
| series | Siriraj Medical Journal |
| spelling | doaj-art-cf09ba512c6e45e481316babef002cea2025-08-20T03:06:51ZengFaculty of Medicine Siriraj HospitalSiriraj Medical Journal2228-80822025-04-0177410.33192/smj.v77i4.272679 Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI)Warut Pongsapich0Narin Ratanaprasert 1Prachya Maneeprasopchoke2Paveena Pithuksurachai3Cheerasook Chongkolwatana4Chanticha Chotigavanich5Paiboon Sureepong6Sunun Ongard7Phawin Keskool8Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, ThailandDepartment of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand Objective: The validation study of the Thai version of the M.D. Anderson Dysphagia Inventory (TH-MDADI) addresses a critical gap in head and neck cancer (HNC) care in Thailand. At leading institutions like Siriraj Hospital, patient-reported outcomes have been historically neglected, with care primarily focusing on routine medical services. This study aimed to validate the TH-MDADI to enhance dysphagia assessment and promote patient centered care. Materials and Methods: In this longitudinal prospective study, 66 HNC patients completed the TH-MDADI and SF-36 at baseline, pre-treatment, and post-treatment at Siriraj Hospital. Psychometric properties were evaluated, including internal consistency (Cronbach’s α), test-retest reliability (intraclass correlation coefficient, ICC), convergent and discriminant validity (correlations with SF-36 domains), and responsiveness (standardized response mean, SRM). Results: The TH-MDADI demonstrated excellent internal consistency (Cronbach’s α = 0.93) and test-retest reliability (ICC = 0.92, 95% CI: 0.88–0.96). Strong correlations with related SF-36 domains (r = 0.64-0.74, p < 0.001) established convergent validity, while weak correlations with unrelated domains confirmed discriminant validity. High responsiveness to change post-treatment was observed, particularly in the Global (SRM = 3.83) and Emotional (SRM = 3.17) subscales. Conclusion: The TH-MDADI demonstrates robust psychometric properties, establishing its value as a reliable tool for assessing dysphagia-related quality of life in Thai HNC patients. This validation represents a significant advancement in Thai cancer care, addressing the historical neglect of patient-reported outcomes. By providing clinicians with a validated assessment instrument, this study promotes a more systematic, patient-centered approach to HNC treatment in Thailand. https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/272679Head and neck cancerMDADISF-36health-related quality of life |
| spellingShingle | Warut Pongsapich Narin Ratanaprasert Prachya Maneeprasopchoke Paveena Pithuksurachai Cheerasook Chongkolwatana Chanticha Chotigavanich Paiboon Sureepong Sunun Ongard Phawin Keskool Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI) Siriraj Medical Journal Head and neck cancer MDADI SF-36 health-related quality of life |
| title | Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI) |
| title_full | Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI) |
| title_fullStr | Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI) |
| title_full_unstemmed | Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI) |
| title_short | Assessing Dysphagia in Head and Neck Cancer Patients: Validation and Cultural Adaptation of the Thai M.D. Anderson Dysphagia Inventory (TH-MDADI) |
| title_sort | assessing dysphagia in head and neck cancer patients validation and cultural adaptation of the thai m d anderson dysphagia inventory th mdadi |
| topic | Head and neck cancer MDADI SF-36 health-related quality of life |
| url | https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/272679 |
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