Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections?
Peritoneal dialysis-related infections are important morbidity/mortality causes, being staphylococci the most prevalent agents. Since Staphylococcus aureus nasopharynx carriage is a known risk factor for PD infections and the oral cavity is a starting point for systemic diseases development, we aime...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2018/5789094 |
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| author | Liliana Simões-Silva Susana Ferreira Carla Santos-Araujo Margarida Tabaio Manuel Pestana Isabel Soares-Silva Benedita Sampaio-Maia |
| author_facet | Liliana Simões-Silva Susana Ferreira Carla Santos-Araujo Margarida Tabaio Manuel Pestana Isabel Soares-Silva Benedita Sampaio-Maia |
| author_sort | Liliana Simões-Silva |
| collection | DOAJ |
| description | Peritoneal dialysis-related infections are important morbidity/mortality causes, being staphylococci the most prevalent agents. Since Staphylococcus aureus nasopharynx carriage is a known risk factor for PD infections and the oral cavity is a starting point for systemic diseases development, we aimed at comparing the oral staphylococci colonization between PD patients and controls and studying the association with PD-related infections. Saliva samples were plated in Mannitol salt, and isolates were identified by DnaJ gene sequencing. Staphylococci PD-related infections were recorded throughout the 4-year period following sample collection. Staphylococcus colonization was present in >90% of the samples from both groups (a total of nine species identified). PD patients presented less diversity and less prevalence of multispecies Staphylococcus colonization. Although all patients presenting Staphylococcus epidermidis PD-related infections were also colonized in the oral cavity by the same agent, only 1 out of 7 patients with ESI caused by S. aureus presented S. aureus oral colonization. Staphylococci are highly prevalent in the oral cavity of both groups, although PD patients presented less species diversity. The association between oral Staphylococcus carriage and PD-related infections was present for S. epidermidis but was almost inexistent for S. aureus, so, further studies are still necessary to evaluate the infectious potential of oral Staphylococcus carriage in PD. |
| format | Article |
| id | doaj-art-cf0484ccc72a4288a1723be8fc671ee6 |
| institution | OA Journals |
| issn | 1712-9532 1918-1493 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-cf0484ccc72a4288a1723be8fc671ee62025-08-20T02:19:30ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932018-01-01201810.1155/2018/57890945789094Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections?Liliana Simões-Silva0Susana Ferreira1Carla Santos-Araujo2Margarida Tabaio3Manuel Pestana4Isabel Soares-Silva5Benedita Sampaio-Maia6i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, PortugalFaculdade de Medicina Dentária, Universidade do Porto, Porto, PortugalDepartamento de Nefrologia, Centro Hospitalar de São João, EPE, Porto, PortugalFaculdade de Medicina Dentária, Universidade do Porto, Porto, Portugali3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugali3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugali3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, PortugalPeritoneal dialysis-related infections are important morbidity/mortality causes, being staphylococci the most prevalent agents. Since Staphylococcus aureus nasopharynx carriage is a known risk factor for PD infections and the oral cavity is a starting point for systemic diseases development, we aimed at comparing the oral staphylococci colonization between PD patients and controls and studying the association with PD-related infections. Saliva samples were plated in Mannitol salt, and isolates were identified by DnaJ gene sequencing. Staphylococci PD-related infections were recorded throughout the 4-year period following sample collection. Staphylococcus colonization was present in >90% of the samples from both groups (a total of nine species identified). PD patients presented less diversity and less prevalence of multispecies Staphylococcus colonization. Although all patients presenting Staphylococcus epidermidis PD-related infections were also colonized in the oral cavity by the same agent, only 1 out of 7 patients with ESI caused by S. aureus presented S. aureus oral colonization. Staphylococci are highly prevalent in the oral cavity of both groups, although PD patients presented less species diversity. The association between oral Staphylococcus carriage and PD-related infections was present for S. epidermidis but was almost inexistent for S. aureus, so, further studies are still necessary to evaluate the infectious potential of oral Staphylococcus carriage in PD.http://dx.doi.org/10.1155/2018/5789094 |
| spellingShingle | Liliana Simões-Silva Susana Ferreira Carla Santos-Araujo Margarida Tabaio Manuel Pestana Isabel Soares-Silva Benedita Sampaio-Maia Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections? Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections? |
| title_full | Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections? |
| title_fullStr | Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections? |
| title_full_unstemmed | Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections? |
| title_short | Oral Colonization of Staphylococcus Species in a Peritoneal Dialysis Population: A Possible Reservoir for PD-Related Infections? |
| title_sort | oral colonization of staphylococcus species in a peritoneal dialysis population a possible reservoir for pd related infections |
| url | http://dx.doi.org/10.1155/2018/5789094 |
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