Choline alleviates cognitive impairment in sleep-deprived young mice via reducing neuroinflammation and altering phospholipidomic profile

Cognitive impairment resulting from insufficient sleep poses a significant public health concern, particularly in children. The effects and mechanisms of choline on cognitive impairment caused by sleep deprivation are unknown. Chronic sleep deprivation is induced in young mice in this study, followe...

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Main Authors:	Si-Yu Huang, Zhi-Jun Yang, Jin Cheng, Hang-Yu Li, Si Chen, Zi-Hui Huang, Jie-Dong Chen, Ruo-Gu Xiong, Meng-Tao Yang, Chen Wang, Meng-Chu Li, Shuang Song, Wen-Ge Huang, Dong-Liang Wang, Hua-Bin Li, Qiu-Ye Lan
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Series:	Redox Biology
Subjects:	Choline Sleep deprivation Cognitive impairment Neuroinflammation Magnetic resonance imaging Phospholipidomics
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231725000916
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