Variants of β-lactamase-encoding genes are disseminated by multiple genetically distinct lineages of bloodstream Escherichia coli

Variants of β-lactamase-encoding genes are disseminated by multiple genetically distinct lineages of bloodstream Escherichia coli

Abstract Background Escherichia coli is a major cause of bloodstream infections (BSI), which can lead to life-threatening organ dysfunction. We determined the genomic characteristics of E. coli implicated in BSI and the spread of antimicrobial resistance (AMR). Methods We carried out in vitro antimi...

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Main Authors: Stephanie S. R. Souza, Kathryn R. Piper, Odion O. Ikhimiukor, Michael M. Marcovici, Nicole I. Zac Soligno, Ashley J. Harmon, Elissa M. Eckhardt, Nisalda Carreiro, Adrienne A. Workman, Isabella W. Martin, Cheryl P. Andam
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-025-00972-x
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