Can Bisphenols Alter the Inflammation Process?
This review’s main purpose is to draw attention to the possible influence of widely used bisphenols on the inflammatory process. Bisphenols are endocrine-disrupting chemicals that are produced worldwide in great quantities. From this point of view, it is very important to clarify their influence on...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/15/5/782 |
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| author | Denis Bazany Hana Greifova Lucia Zuscikova Katarina Tokarova Tomas Jambor Anton Kovacik Norbert Lukac |
| author_facet | Denis Bazany Hana Greifova Lucia Zuscikova Katarina Tokarova Tomas Jambor Anton Kovacik Norbert Lukac |
| author_sort | Denis Bazany |
| collection | DOAJ |
| description | This review’s main purpose is to draw attention to the possible influence of widely used bisphenols on the inflammatory process. Bisphenols are endocrine-disrupting chemicals that are produced worldwide in great quantities. From this point of view, it is very important to clarify their influence on innate immune reactions, which protect the integrity of the body against the action of various pathogens on a daily basis. The inflammation process consists of several key factors that are produced at different levels of this reaction. Each of these levels can be affected by endocrine disruptors, from the point of view of modifying either the immune system cells that intervene in this process or the way in which they produce inflammatory mediators. The development of new recommendations for the use of bisphenols is a complex issue given their influence on inflammatory processes. Because the immune system and immune response are so intricate, bisphenols may pose more risk to humans than is presently recognized. This paper discusses the classification of bisphenols, the fundamental mechanism of inflammation, the characterization of inflammatory mediators, and the current knowledge of the molecular mechanisms behind the impact of bisphenols on the inflammatory response. |
| format | Article |
| id | doaj-art-ceeeac04b671489fb2aaa2ec09910dd4 |
| institution | Kabale University |
| issn | 2075-1729 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj-art-ceeeac04b671489fb2aaa2ec09910dd42025-08-20T03:48:02ZengMDPI AGLife2075-17292025-05-0115578210.3390/life15050782Can Bisphenols Alter the Inflammation Process?Denis Bazany0Hana Greifova1Lucia Zuscikova2Katarina Tokarova3Tomas Jambor4Anton Kovacik5Norbert Lukac6Institute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, SlovakiaAgroBioTech Research Centre, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, SlovakiaInstitute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, SlovakiaInstitute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, SlovakiaInstitute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, SlovakiaInstitute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, SlovakiaInstitute of Applied Biology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, SlovakiaThis review’s main purpose is to draw attention to the possible influence of widely used bisphenols on the inflammatory process. Bisphenols are endocrine-disrupting chemicals that are produced worldwide in great quantities. From this point of view, it is very important to clarify their influence on innate immune reactions, which protect the integrity of the body against the action of various pathogens on a daily basis. The inflammation process consists of several key factors that are produced at different levels of this reaction. Each of these levels can be affected by endocrine disruptors, from the point of view of modifying either the immune system cells that intervene in this process or the way in which they produce inflammatory mediators. The development of new recommendations for the use of bisphenols is a complex issue given their influence on inflammatory processes. Because the immune system and immune response are so intricate, bisphenols may pose more risk to humans than is presently recognized. This paper discusses the classification of bisphenols, the fundamental mechanism of inflammation, the characterization of inflammatory mediators, and the current knowledge of the molecular mechanisms behind the impact of bisphenols on the inflammatory response.https://www.mdpi.com/2075-1729/15/5/782inflammationbisphenolsendocrine disrupting chemicalsprostaglandinsinterleukins |
| spellingShingle | Denis Bazany Hana Greifova Lucia Zuscikova Katarina Tokarova Tomas Jambor Anton Kovacik Norbert Lukac Can Bisphenols Alter the Inflammation Process? Life inflammation bisphenols endocrine disrupting chemicals prostaglandins interleukins |
| title | Can Bisphenols Alter the Inflammation Process? |
| title_full | Can Bisphenols Alter the Inflammation Process? |
| title_fullStr | Can Bisphenols Alter the Inflammation Process? |
| title_full_unstemmed | Can Bisphenols Alter the Inflammation Process? |
| title_short | Can Bisphenols Alter the Inflammation Process? |
| title_sort | can bisphenols alter the inflammation process |
| topic | inflammation bisphenols endocrine disrupting chemicals prostaglandins interleukins |
| url | https://www.mdpi.com/2075-1729/15/5/782 |
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