A novel RP-HPLC stability-indicating method for simultaneous estimation of Niraparib and Abiraterone in synthetic mixtures and combined tablet formulations

A novel RP-HPLC stability-indicating method for simultaneous estimation of Niraparib and Abiraterone in synthetic mixtures and combined tablet formulations

Abstract Niraparib and Abiraterone in a combined dosage form offer a fortunate regimen for treating cancers, mainly those resistant to conventional therapies cast in cancer treatment. The present study intends to develop a novel RP-HPLC method for simultaneously estimating Niraparib and Abiraterone...

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Bibliographic Details
Main Authors: Krishnaphanisri Ponnekanti, Ramreddy Godela, Divya Reddy Solipeta, K. Sujatha, Durga Prasad Beda
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Applied Sciences
Subjects:
Niraparib
Abiraterone
Stability-indicating
RP-HPLC
Isocratic elution
Forced degradation
Online Access:https://doi.org/10.1007/s42452-025-06930-5
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