Recent development of nanotechnology-based approaches for gynecologic cancer therapy

Gynecological cancer is a life-threatening malignancy among women. Traditional therapies, including chemotherapy, often face challenges in terms of chemotherapeutic drug solubility and resistance, specificity, tumor site targeting, and toxicity to healthy tissues, leading to shortened efficacy and u...

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Main Authors: Gangaraju Gedda, Yoo-Jin Park, Myung-Geol Pang
Format: Article
Language:English
Published: Korean Society of Obstetrics and Gynecology 2025-01-01
Series:Obstetrics & Gynecology Science
Subjects:
Online Access:http://www.ogscience.org/upload/pdf/ogs-24180.pdf
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author Gangaraju Gedda
Yoo-Jin Park
Myung-Geol Pang
author_facet Gangaraju Gedda
Yoo-Jin Park
Myung-Geol Pang
author_sort Gangaraju Gedda
collection DOAJ
description Gynecological cancer is a life-threatening malignancy among women. Traditional therapies, including chemotherapy, often face challenges in terms of chemotherapeutic drug solubility and resistance, specificity, tumor site targeting, and toxicity to healthy tissues, leading to shortened efficacy and unfavorable patient outcomes and survival rates in patients with gynecologic malignancies. Recently, nanotechnology-based therapeutic methods such as targeted drug delivery and phototherapies have emerged as an appropriate alternative to overcome issues associated with traditional therapeutic methods. Specifically, nanomaterials and nanomaterial-based methods enhance the delivery of therapeutic/targeting agents to tumor sites and cellular uptakes and improve the tumor-suppressing effect. This review aims to provide an overview and future perspective on the potential impact of nanotechnology-based therapeutic methods for effective therapies for gynecologic cancer.
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publisher Korean Society of Obstetrics and Gynecology
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series Obstetrics & Gynecology Science
spelling doaj-art-cecbbce42bf943268440a1a331ff80482025-08-20T02:26:28ZengKorean Society of Obstetrics and GynecologyObstetrics & Gynecology Science2287-85802025-01-01681182910.5468/ogs.241808851Recent development of nanotechnology-based approaches for gynecologic cancer therapyGangaraju Gedda0Yoo-Jin Park1Myung-Geol Pang2 Department of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong, Korea Department of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong, Korea Department of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong, KoreaGynecological cancer is a life-threatening malignancy among women. Traditional therapies, including chemotherapy, often face challenges in terms of chemotherapeutic drug solubility and resistance, specificity, tumor site targeting, and toxicity to healthy tissues, leading to shortened efficacy and unfavorable patient outcomes and survival rates in patients with gynecologic malignancies. Recently, nanotechnology-based therapeutic methods such as targeted drug delivery and phototherapies have emerged as an appropriate alternative to overcome issues associated with traditional therapeutic methods. Specifically, nanomaterials and nanomaterial-based methods enhance the delivery of therapeutic/targeting agents to tumor sites and cellular uptakes and improve the tumor-suppressing effect. This review aims to provide an overview and future perspective on the potential impact of nanotechnology-based therapeutic methods for effective therapies for gynecologic cancer.http://www.ogscience.org/upload/pdf/ogs-24180.pdfgynecologynanotechnologydrug delivery systemphotodynamic therapyphotothermal therapy
spellingShingle Gangaraju Gedda
Yoo-Jin Park
Myung-Geol Pang
Recent development of nanotechnology-based approaches for gynecologic cancer therapy
Obstetrics & Gynecology Science
gynecology
nanotechnology
drug delivery system
photodynamic therapy
photothermal therapy
title Recent development of nanotechnology-based approaches for gynecologic cancer therapy
title_full Recent development of nanotechnology-based approaches for gynecologic cancer therapy
title_fullStr Recent development of nanotechnology-based approaches for gynecologic cancer therapy
title_full_unstemmed Recent development of nanotechnology-based approaches for gynecologic cancer therapy
title_short Recent development of nanotechnology-based approaches for gynecologic cancer therapy
title_sort recent development of nanotechnology based approaches for gynecologic cancer therapy
topic gynecology
nanotechnology
drug delivery system
photodynamic therapy
photothermal therapy
url http://www.ogscience.org/upload/pdf/ogs-24180.pdf
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AT myunggeolpang recentdevelopmentofnanotechnologybasedapproachesforgynecologiccancertherapy