Recent advances in mitochondrial replacement therapy and its future expectations
Abstract The prevention of mitochondrial diseases is particularly important due to the lack of specific therapies. Therefore, mitochondrial replacement therapy (MRT) is expected to be a technology to prevent mitochondrial diseases. Admittedly, this technology sparked a lot of controversy and discuss...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-02-01
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| Series: | Clinical and Translational Discovery |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ctd2.70010 |
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| Summary: | Abstract The prevention of mitochondrial diseases is particularly important due to the lack of specific therapies. Therefore, mitochondrial replacement therapy (MRT) is expected to be a technology to prevent mitochondrial diseases. Admittedly, this technology sparked a lot of controversy and discussion. In this article, we review the recent advances in MRT, discuss its safety and ethical issues, and finally explore its potential to completely block the inheritance of mitochondrial diseases. |
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| ISSN: | 2768-0622 |