Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health

A natural product-based dietary approach could offer a safe and effective method for slowing down or preventing age-related deterioration in skin appearance and function, including issues like hyperpigmentation, dryness and wrinkles. Proliv Essence-3 (PE3) is a botanical beverage, meant for oral con...

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Main Authors: Nor Hafizah Zakaria, Fadzilah Adibah Abdul Majid, Anis Fadhlina, Siti Noorwanie Abdul Hamid, Mohd Nur Nasyriq Anuar, Tengku Nurfarhana Tengku Aziz
Format: Article
Language:English
Published: Maximum Academic Press 2024-01-01
Series:Beverage Plant Research
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Online Access:https://www.maxapress.com/article/doi/10.48130/bpr-0024-0008
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author Nor Hafizah Zakaria
Fadzilah Adibah Abdul Majid
Anis Fadhlina
Siti Noorwanie Abdul Hamid
Mohd Nur Nasyriq Anuar
Tengku Nurfarhana Tengku Aziz
author_facet Nor Hafizah Zakaria
Fadzilah Adibah Abdul Majid
Anis Fadhlina
Siti Noorwanie Abdul Hamid
Mohd Nur Nasyriq Anuar
Tengku Nurfarhana Tengku Aziz
author_sort Nor Hafizah Zakaria
collection DOAJ
description A natural product-based dietary approach could offer a safe and effective method for slowing down or preventing age-related deterioration in skin appearance and function, including issues like hyperpigmentation, dryness and wrinkles. Proliv Essence-3 (PE3) is a botanical beverage, meant for oral consumption with a unique formulation of three selected fruit extracts, Momordica charantia, Malus domestica, and Psidium guajava. Its purpose is to enhance both skin health and overall well-being from within. Proximate composition, presence of gallic acid and antioxidant activity of PE3 extract were determined. Elastase and tyrosinase inhibition assays were employed to investigate the anti-aging and whitening effects, respectively. The in vitro scratch assay and epidermal growth factor (EGF) assay were carried out to evaluate skin cell growth promotion and rejuvenation. The cytotoxicity analysis was carried out via neutral red uptake. The proximate analysis revealed that the product had a high moisture content and low amounts of calories. High-performance liquid chromatography (HPLC) analysis estimated 11.22 mg of gallic acid in 1 g of PE3 extract. PE3 exhibited a DPPH-IC50 value of 148.60 ± 1.52 μg/mL and an ABTS-IC50 value of 91.18 ± 1.15 μg/mL. The IC50 values for tyrosinase and elastase inhibition assays were 160.20 ± 1.81 μg/mL and 65.49 ± 0.38 μg/mL, respectively. PE3 was also discovered to be non-cytotoxic, and it enhanced the migration and proliferation of HSF1184 cells. EGF secretion was detected in PE3-treated HSF1184. This study provided preliminary evidence supporting the potential of PE3 as a nutricosmetical botanical beverage for promoting skin beautification and general health.
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spelling doaj-art-cec0d73cd42645ef8474ca0d67d1333e2025-08-20T03:18:31ZengMaximum Academic PressBeverage Plant Research2769-21082024-01-01411910.48130/bpr-0024-0008bpr-0024-0008Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general healthNor Hafizah Zakaria0Fadzilah Adibah Abdul Majid1Anis Fadhlina2Siti Noorwanie Abdul Hamid3Mohd Nur Nasyriq Anuar4Tengku Nurfarhana Tengku Aziz5Institute of Climate Adaptation and Marine Biotechnology (ICAMB), Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, MalaysiaInstitute of Climate Adaptation and Marine Biotechnology (ICAMB), Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, MalaysiaDepartment of Fundamental Dental and Medical Sciences, Kulliyyah of Dentistry, International Islamic University Malaysia, 25200 Kuantan, Pahang, MalaysiaBioprocess and Polymer Engineering Department, School of Chemical and Energy Engineering, Faculty of Engineering, Universiti Teknologi Malaysia, 81030 Johor Bahru, Johor, MalaysiaProliv Life Sciences Sdn Bhd, Taman Ukay Bistari, 68000 Ampang, Selangor, MalaysiaInstitute of Climate Adaptation and Marine Biotechnology (ICAMB), Universiti Malaysia Terengganu, 21030 Kuala Nerus, Terengganu, MalaysiaA natural product-based dietary approach could offer a safe and effective method for slowing down or preventing age-related deterioration in skin appearance and function, including issues like hyperpigmentation, dryness and wrinkles. Proliv Essence-3 (PE3) is a botanical beverage, meant for oral consumption with a unique formulation of three selected fruit extracts, Momordica charantia, Malus domestica, and Psidium guajava. Its purpose is to enhance both skin health and overall well-being from within. Proximate composition, presence of gallic acid and antioxidant activity of PE3 extract were determined. Elastase and tyrosinase inhibition assays were employed to investigate the anti-aging and whitening effects, respectively. The in vitro scratch assay and epidermal growth factor (EGF) assay were carried out to evaluate skin cell growth promotion and rejuvenation. The cytotoxicity analysis was carried out via neutral red uptake. The proximate analysis revealed that the product had a high moisture content and low amounts of calories. High-performance liquid chromatography (HPLC) analysis estimated 11.22 mg of gallic acid in 1 g of PE3 extract. PE3 exhibited a DPPH-IC50 value of 148.60 ± 1.52 μg/mL and an ABTS-IC50 value of 91.18 ± 1.15 μg/mL. The IC50 values for tyrosinase and elastase inhibition assays were 160.20 ± 1.81 μg/mL and 65.49 ± 0.38 μg/mL, respectively. PE3 was also discovered to be non-cytotoxic, and it enhanced the migration and proliferation of HSF1184 cells. EGF secretion was detected in PE3-treated HSF1184. This study provided preliminary evidence supporting the potential of PE3 as a nutricosmetical botanical beverage for promoting skin beautification and general health.https://www.maxapress.com/article/doi/10.48130/bpr-0024-0008proliv essence-3botanical beveragenutraceuticalskin beautificationanti-aging
spellingShingle Nor Hafizah Zakaria
Fadzilah Adibah Abdul Majid
Anis Fadhlina
Siti Noorwanie Abdul Hamid
Mohd Nur Nasyriq Anuar
Tengku Nurfarhana Tengku Aziz
Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health
Beverage Plant Research
proliv essence-3
botanical beverage
nutraceutical
skin beautification
anti-aging
title Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health
title_full Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health
title_fullStr Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health
title_full_unstemmed Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health
title_short Proliv Essence-3 (PE3): a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health
title_sort proliv essence 3 pe3 a nutricosmetic botanical blend as a dietary beverage for skin wellness and general health
topic proliv essence-3
botanical beverage
nutraceutical
skin beautification
anti-aging
url https://www.maxapress.com/article/doi/10.48130/bpr-0024-0008
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