Tumor budding as an indicator of prognosis in locally advanced rectal cancer after neoadjuvant chemoradiotherapy: a systematic review and meta-analysis

Tumor budding as an indicator of prognosis in locally advanced rectal cancer after neoadjuvant chemoradiotherapy: a systematic review and meta-analysis

IntroductionTumor budding (TB) is recognized as a complementary prognostic factor for colorectal cancer. However, data on its impact on the survival of patients undergoing neoadjuvant chemoradiotherapy (nCRT) remain limited. This study aims to investigate the role of TB in disease-free survival (DFS...

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Bibliographic Details
Main Authors: Azita Rafiee, Parto Nasri, Afshin Moradi, Paridokht Karimian
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Oncology
Subjects:
rectal neoplasm
neoadjuvant therapy
tumor budding
prognosis
colon cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1429319/full
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