The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament

Objectives. To evaluate the influence of dentine on the pH of different medications in standardized simulated canals. Materials and Methods. Forty resin blocks were divided into groups with and without dentine powder, as follows: 2% chlorhexidine gel; 2% chlorhexidine gel associated with calcium hyd...

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Main Authors: Ceci Nunes Carvalho, Laila Gonzales Freire, Alexandre Pinheiro Lima de Carvalho, Evandro Luiz Siqueira, José Bauer, Giovana Cunha Gritti, Juliana Pereira de Souza, Giulio Gavini
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2015/686259
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author Ceci Nunes Carvalho
Laila Gonzales Freire
Alexandre Pinheiro Lima de Carvalho
Evandro Luiz Siqueira
José Bauer
Giovana Cunha Gritti
Juliana Pereira de Souza
Giulio Gavini
author_facet Ceci Nunes Carvalho
Laila Gonzales Freire
Alexandre Pinheiro Lima de Carvalho
Evandro Luiz Siqueira
José Bauer
Giovana Cunha Gritti
Juliana Pereira de Souza
Giulio Gavini
author_sort Ceci Nunes Carvalho
collection DOAJ
description Objectives. To evaluate the influence of dentine on the pH of different medications in standardized simulated canals. Materials and Methods. Forty resin blocks were divided into groups with and without dentine powder, as follows: 2% chlorhexidine gel; 2% chlorhexidine gel associated with calcium hydroxide PA; calcium hydroxide PA delivered in propylene glycol 600; and NPG delivered in distilled water. The dentine powder was obtained from the root dentine of bovine teeth and added to the medications. The simulated canals were placed in containers with 1.5 mL of deionized water and pH was monitored in multiple intervals, up to 30 days. The mean pH values were calculated and submitted to statistical analysis using paired Student’s t-test and ANOVA complemented by the Tukey test (p<0.05). Results. There was no statistical difference between the groups with and without dentine powder (p>0.05). The pH values of calcium hydroxide were significantly higher than those of NPG in the first 24 hours (p<0.05). After 7 days, both behaved in a similar manner. Conclusion. The addition of dentine powder to the medications evaluated did not alter the pH of the external solution in any of the time points tested.
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spelling doaj-art-ceaf257fb8a94c23b435a10e2efdd5cf2025-08-20T03:19:39ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/686259686259The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal MedicamentCeci Nunes Carvalho0Laila Gonzales Freire1Alexandre Pinheiro Lima de Carvalho2Evandro Luiz Siqueira3José Bauer4Giovana Cunha Gritti5Juliana Pereira de Souza6Giulio Gavini7University Ceuma, Rua Josué Montello No. 1, Renascença II, 65075-120 São Luís, MA, BrazilSchool of Dentistry, University of São Paulo, Department of Restorative Dentistry, Endodontics Division, Avenida Prof. Lineu Prestes 2227, 05508-000 São Paulo, SP, BrazilSchool of Dentistry, University of São Paulo, Department of Restorative Dentistry, Endodontics Division, Avenida Prof. Lineu Prestes 2227, 05508-000 São Paulo, SP, BrazilSchool of Dentistry, University of São Paulo, Department of Restorative Dentistry, Endodontics Division, Avenida Prof. Lineu Prestes 2227, 05508-000 São Paulo, SP, BrazilDepartment of Dentistry I, School of Dentistry, University Federal of Maranhão (UFMA), Avenida dos Portugueses, s/n, 65085-680 São Luís, MA, BrazilUniversity Ceuma, Rua Josué Montello No. 1, Renascença II, 65075-120 São Luís, MA, BrazilCenter of Materials Science and Technology, Energy and Nuclear Research Institute (IPEN), Avenida Lineu Prestes 2242, Cidade Universitaria, 05588-900 São Paulo, SP, BrazilSchool of Dentistry, University of São Paulo, Department of Restorative Dentistry, Endodontics Division, Avenida Prof. Lineu Prestes 2227, 05508-000 São Paulo, SP, BrazilObjectives. To evaluate the influence of dentine on the pH of different medications in standardized simulated canals. Materials and Methods. Forty resin blocks were divided into groups with and without dentine powder, as follows: 2% chlorhexidine gel; 2% chlorhexidine gel associated with calcium hydroxide PA; calcium hydroxide PA delivered in propylene glycol 600; and NPG delivered in distilled water. The dentine powder was obtained from the root dentine of bovine teeth and added to the medications. The simulated canals were placed in containers with 1.5 mL of deionized water and pH was monitored in multiple intervals, up to 30 days. The mean pH values were calculated and submitted to statistical analysis using paired Student’s t-test and ANOVA complemented by the Tukey test (p<0.05). Results. There was no statistical difference between the groups with and without dentine powder (p>0.05). The pH values of calcium hydroxide were significantly higher than those of NPG in the first 24 hours (p<0.05). After 7 days, both behaved in a similar manner. Conclusion. The addition of dentine powder to the medications evaluated did not alter the pH of the external solution in any of the time points tested.http://dx.doi.org/10.1155/2015/686259
spellingShingle Ceci Nunes Carvalho
Laila Gonzales Freire
Alexandre Pinheiro Lima de Carvalho
Evandro Luiz Siqueira
José Bauer
Giovana Cunha Gritti
Juliana Pereira de Souza
Giulio Gavini
The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament
The Scientific World Journal
title The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament
title_full The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament
title_fullStr The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament
title_full_unstemmed The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament
title_short The Influence of Dentine on the pH of Calcium Hydroxide, Chlorhexidine Gel, and Experimental Bioactive Glass-Based Root Canal Medicament
title_sort influence of dentine on the ph of calcium hydroxide chlorhexidine gel and experimental bioactive glass based root canal medicament
url http://dx.doi.org/10.1155/2015/686259
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