Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan
Purpose: Medication-related osteonecrosis of the jaw (MRONJ) caused by bisphosphonates (BPs) and denosumab (Dmab) is still a major oral adverse event caused by cancer treatment and may be under-recognized by private dental services. With the aim of reducing the prevalence of MRONJ, this study, which...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2024-10-01
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| Series: | Gerontology and Geriatric Medicine |
| Online Access: | https://doi.org/10.1177/23337214241292794 |
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| author | Yosuke Iijima DDS, PhD Miki Yamada DDS Mai Amano MS Saya Watanabe MS Miki Fujimaru BS Ayako Uematsu BS Shunsuke Hino DDS, PhD Motohiko Sano PhD Norio Horie DDS, PhD Hiroshi Sakagami PhD Takahiro Kaneko DDS, PhD |
| author_facet | Yosuke Iijima DDS, PhD Miki Yamada DDS Mai Amano MS Saya Watanabe MS Miki Fujimaru BS Ayako Uematsu BS Shunsuke Hino DDS, PhD Motohiko Sano PhD Norio Horie DDS, PhD Hiroshi Sakagami PhD Takahiro Kaneko DDS, PhD |
| author_sort | Yosuke Iijima DDS, PhD |
| collection | DOAJ |
| description | Purpose: Medication-related osteonecrosis of the jaw (MRONJ) caused by bisphosphonates (BPs) and denosumab (Dmab) is still a major oral adverse event caused by cancer treatment and may be under-recognized by private dental services. With the aim of reducing the prevalence of MRONJ, this study, which is a pilot study for a planned future large-scale survey, compared knowledge about MRONJ between dental hygienists (DHs) in private dental clinics and those in cancer center hospitals. Methods: We conducted a questionnaire-based survey regarding MRONJ between 1 November 2023 and 31 January 2024 on DHs at a cancer base hospital and a private clinic in Saitama, Japan. We statistically analyzed the data collected using the χ 2 test or Fisher’s exact test with the level of significance set at 5%. Results: This study included 10 in-hospital and 53 private clinic DHs. The in-hospital DHs had appropriate knowledge of MRONJ. However, compared with the in-hospital DHs, although the private clinic DHs knew that BPs are used for osteoporosis, significantly fewer had knowledge of Dmab ( p < .001) or knew that BPs and Dmab could also be used to treat cancer (both p < .001). In addition, few private clinic DHs were aware of MRONJ cases refractory to antibiotic treatment alone ( p = .012). Conclusion: These findings suggest that private clinic DHs have less knowledge of MRONJ than those in cancer base hospitals. |
| format | Article |
| id | doaj-art-cea197e083464948a9fbe69e5cd66c95 |
| institution | OA Journals |
| issn | 2333-7214 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Gerontology and Geriatric Medicine |
| spelling | doaj-art-cea197e083464948a9fbe69e5cd66c952025-08-20T01:47:25ZengSAGE PublishingGerontology and Geriatric Medicine2333-72142024-10-011010.1177/23337214241292794Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in JapanYosuke Iijima DDS, PhD0Miki Yamada DDS1Mai Amano MS2Saya Watanabe MS3Miki Fujimaru BS4Ayako Uematsu BS5Shunsuke Hino DDS, PhD6Motohiko Sano PhD7Norio Horie DDS, PhD8Hiroshi Sakagami PhD9Takahiro Kaneko DDS, PhD10Department of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JapanDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JapanDivision of Applied Pharmaceutical Education and Research, Hoshi University, Tokyo, JapanDivision of Applied Pharmaceutical Education and Research, Hoshi University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JapanDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JapanDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JapanDivision of Applied Pharmaceutical Education and Research, Hoshi University, Tokyo, JapanDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JapanMeikai University Research Institute of Odontology (M-RIO), Saitama, JapanDepartment of Oral and Maxillofacial Surgery, Saitama Medical Center, Saitama Medical University, Saitama, JapanPurpose: Medication-related osteonecrosis of the jaw (MRONJ) caused by bisphosphonates (BPs) and denosumab (Dmab) is still a major oral adverse event caused by cancer treatment and may be under-recognized by private dental services. With the aim of reducing the prevalence of MRONJ, this study, which is a pilot study for a planned future large-scale survey, compared knowledge about MRONJ between dental hygienists (DHs) in private dental clinics and those in cancer center hospitals. Methods: We conducted a questionnaire-based survey regarding MRONJ between 1 November 2023 and 31 January 2024 on DHs at a cancer base hospital and a private clinic in Saitama, Japan. We statistically analyzed the data collected using the χ 2 test or Fisher’s exact test with the level of significance set at 5%. Results: This study included 10 in-hospital and 53 private clinic DHs. The in-hospital DHs had appropriate knowledge of MRONJ. However, compared with the in-hospital DHs, although the private clinic DHs knew that BPs are used for osteoporosis, significantly fewer had knowledge of Dmab ( p < .001) or knew that BPs and Dmab could also be used to treat cancer (both p < .001). In addition, few private clinic DHs were aware of MRONJ cases refractory to antibiotic treatment alone ( p = .012). Conclusion: These findings suggest that private clinic DHs have less knowledge of MRONJ than those in cancer base hospitals.https://doi.org/10.1177/23337214241292794 |
| spellingShingle | Yosuke Iijima DDS, PhD Miki Yamada DDS Mai Amano MS Saya Watanabe MS Miki Fujimaru BS Ayako Uematsu BS Shunsuke Hino DDS, PhD Motohiko Sano PhD Norio Horie DDS, PhD Hiroshi Sakagami PhD Takahiro Kaneko DDS, PhD Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan Gerontology and Geriatric Medicine |
| title | Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan |
| title_full | Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan |
| title_fullStr | Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan |
| title_full_unstemmed | Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan |
| title_short | Dental Hygienists’ Awareness of Medication-Related Osteonecrosis of the Jaw in Private Dental Clinics in Japan |
| title_sort | dental hygienists awareness of medication related osteonecrosis of the jaw in private dental clinics in japan |
| url | https://doi.org/10.1177/23337214241292794 |
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