Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea

Cicatricial tracheal stenosis is an urgent matter in thoracic surgery and otolaryngology. The main causes of cicatricial stenosis of the trachea is orotracheal intubation, tracheostomy and neck injuries with damage to the trachea. One of the factors that complicate this disease course is addition of...

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Main Authors: I. S. Kurganskiy, V. N. Makhutov, S. A. Lepekhova, A. V. Vetokhina, E. V. Koval, T. V. Fadeeva, E. O. Inozemtsev, E. G. Grigoryev
Format: Article
Language:Russian
Published: Scientific Сentre for Family Health and Human Reproduction Problems 2017-05-01
Series:Acta Biomedica Scientifica
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Online Access:https://www.actabiomedica.ru/jour/article/view/383
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author I. S. Kurganskiy
V. N. Makhutov
S. A. Lepekhova
A. V. Vetokhina
E. V. Koval
T. V. Fadeeva
E. O. Inozemtsev
E. G. Grigoryev
author_facet I. S. Kurganskiy
V. N. Makhutov
S. A. Lepekhova
A. V. Vetokhina
E. V. Koval
T. V. Fadeeva
E. O. Inozemtsev
E. G. Grigoryev
author_sort I. S. Kurganskiy
collection DOAJ
description Cicatricial tracheal stenosis is an urgent matter in thoracic surgery and otolaryngology. The main causes of cicatricial stenosis of the trachea is orotracheal intubation, tracheostomy and neck injuries with damage to the trachea. One of the factors that complicate this disease course is addition of nosocomial infection. We conducted a retrospective study of medical records of 33 patients treated in the thoracic surgery department of Irkutsk Regional Clinical Hospital diagnosed with cicatricial stenosis of trachea for the period from 2011 to 2013. 75 % of patients with cicatricial stenosis of trachea were men of working age up to 50 years old. We evaluated the results of bacteriological examination of detachable tracheobronchial tree. The bacteriological examination of the patients with cicatricial stenosis of trachea often exhibited hospital microflora in the form of Pseudomonas aeruginosa, Streptococcus viridans, Staphylococcus aureus. Associations of microorganisms represent this microflora in 84.4 %. During the antibiotic sensitivity examination, the low effectiveness of commonly used antimicrobials was revealed. The choices in treatment of the patients with cicatricial stenosis of trachea are: colistin, polimeksin, imipenem, meropenem, vancomycin, sulperazon. These results indicate that microbiological monitoring is necessary to detect major pathogens and their antibiotic resistance level at cicatricial stenosis of the trachea.
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issn 2541-9420
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language Russian
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publisher Scientific Сentre for Family Health and Human Reproduction Problems
record_format Article
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spelling doaj-art-ce9a5850e44f435d92dccdb15337ba672025-08-20T03:56:54ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962017-05-0123182210.12737/article_59f035f9133e24.91818541383Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of tracheaI. S. Kurganskiy0V. N. Makhutov1S. A. Lepekhova2A. V. Vetokhina3E. V. Koval4T. V. Fadeeva5E. O. Inozemtsev6E. G. Grigoryev7Irkutsk Scientific Center of Surgery and TraumatologyIrkutsk Regional Clinical HospitalIrkutsk Scientific Center of Surgery and Traumatology; Irkutsk Scientific Center SB RAS; Irkutsk State Medical UniversityIrkutsk Regional Clinical HospitalIrkutsk Scientific Center of Surgery and TraumatologyIrkutsk Scientific Center of Surgery and TraumatologyIrkutsk Scientific Center of Surgery and Traumatology; Irkutsk Regional Clinical HospitalIrkutsk Scientific Center of Surgery and Traumatology; Irkutsk State Medical UniversityCicatricial tracheal stenosis is an urgent matter in thoracic surgery and otolaryngology. The main causes of cicatricial stenosis of the trachea is orotracheal intubation, tracheostomy and neck injuries with damage to the trachea. One of the factors that complicate this disease course is addition of nosocomial infection. We conducted a retrospective study of medical records of 33 patients treated in the thoracic surgery department of Irkutsk Regional Clinical Hospital diagnosed with cicatricial stenosis of trachea for the period from 2011 to 2013. 75 % of patients with cicatricial stenosis of trachea were men of working age up to 50 years old. We evaluated the results of bacteriological examination of detachable tracheobronchial tree. The bacteriological examination of the patients with cicatricial stenosis of trachea often exhibited hospital microflora in the form of Pseudomonas aeruginosa, Streptococcus viridans, Staphylococcus aureus. Associations of microorganisms represent this microflora in 84.4 %. During the antibiotic sensitivity examination, the low effectiveness of commonly used antimicrobials was revealed. The choices in treatment of the patients with cicatricial stenosis of trachea are: colistin, polimeksin, imipenem, meropenem, vancomycin, sulperazon. These results indicate that microbiological monitoring is necessary to detect major pathogens and their antibiotic resistance level at cicatricial stenosis of the trachea.https://www.actabiomedica.ru/jour/article/view/383cicatricial stenosis of tracheamicrobiologyantibiotic therapy
spellingShingle I. S. Kurganskiy
V. N. Makhutov
S. A. Lepekhova
A. V. Vetokhina
E. V. Koval
T. V. Fadeeva
E. O. Inozemtsev
E. G. Grigoryev
Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea
Acta Biomedica Scientifica
cicatricial stenosis of trachea
microbiology
antibiotic therapy
title Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea
title_full Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea
title_fullStr Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea
title_full_unstemmed Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea
title_short Assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea
title_sort assessment of microbial contamination of tracheobronchial tree in patients with cicatrical stenosis of trachea
topic cicatricial stenosis of trachea
microbiology
antibiotic therapy
url https://www.actabiomedica.ru/jour/article/view/383
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