Bullous pemphigoid after Split Skin grafting in vitiligo patient
Bullous pemphigoid (BP) is an autoimmune condition characterized by tense subepidermal blisters commonly seen in old age. Vitiligo is another autoimmune disease associated with loss of melanocytes. Very few cases of coexistence of vitiligo and BP are reported. A split skin graft (SSG) is a surgical...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Pigment International |
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| Online Access: | https://journals.lww.com/10.4103/pigmentinternational_4_23 |
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| _version_ | 1825199211917869056 |
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| author | Siddharth Bhatt Anand Mannu Gourang Paliwal Biju Vasudevan |
| author_facet | Siddharth Bhatt Anand Mannu Gourang Paliwal Biju Vasudevan |
| author_sort | Siddharth Bhatt |
| collection | DOAJ |
| description | Bullous pemphigoid (BP) is an autoimmune condition characterized by tense subepidermal blisters commonly seen in old age. Vitiligo is another autoimmune disease associated with loss of melanocytes. Very few cases of coexistence of vitiligo and BP are reported. A split skin graft (SSG) is a surgical option for stable vitiligo. BP over the SSG is a rare occurrence. We present the case of an elderly individual who developed BP at the site of SSG for vitiligo. Postmanagement of BP the lesion healed with recurrence of vitiligo patch at the same site. This case highlights that surgical intervention without ascertaining the stability of the disease activity may not only preclude the patient to the development of the primary disease but also lead to development of other autoimmune illnesses at the surgical site due to unmasking of the epitope to already circulating antibodies. |
| format | Article |
| id | doaj-art-ce8a0061d7324e3da97063b74c792bd1 |
| institution | Kabale University |
| issn | 2349-5782 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pigment International |
| spelling | doaj-art-ce8a0061d7324e3da97063b74c792bd12025-02-08T05:40:27ZengWolters Kluwer Medknow PublicationsPigment International2349-57822024-12-0111319820010.4103/pigmentinternational_4_23Bullous pemphigoid after Split Skin grafting in vitiligo patientSiddharth BhattAnand MannuGourang PaliwalBiju VasudevanBullous pemphigoid (BP) is an autoimmune condition characterized by tense subepidermal blisters commonly seen in old age. Vitiligo is another autoimmune disease associated with loss of melanocytes. Very few cases of coexistence of vitiligo and BP are reported. A split skin graft (SSG) is a surgical option for stable vitiligo. BP over the SSG is a rare occurrence. We present the case of an elderly individual who developed BP at the site of SSG for vitiligo. Postmanagement of BP the lesion healed with recurrence of vitiligo patch at the same site. This case highlights that surgical intervention without ascertaining the stability of the disease activity may not only preclude the patient to the development of the primary disease but also lead to development of other autoimmune illnesses at the surgical site due to unmasking of the epitope to already circulating antibodies.https://journals.lww.com/10.4103/pigmentinternational_4_23bullous pemphigoidvitiligosplit skin graftinglocalized bullous pemphigoidstability in vitiligo |
| spellingShingle | Siddharth Bhatt Anand Mannu Gourang Paliwal Biju Vasudevan Bullous pemphigoid after Split Skin grafting in vitiligo patient Pigment International bullous pemphigoid vitiligo split skin grafting localized bullous pemphigoid stability in vitiligo |
| title | Bullous pemphigoid after Split Skin grafting in vitiligo patient |
| title_full | Bullous pemphigoid after Split Skin grafting in vitiligo patient |
| title_fullStr | Bullous pemphigoid after Split Skin grafting in vitiligo patient |
| title_full_unstemmed | Bullous pemphigoid after Split Skin grafting in vitiligo patient |
| title_short | Bullous pemphigoid after Split Skin grafting in vitiligo patient |
| title_sort | bullous pemphigoid after split skin grafting in vitiligo patient |
| topic | bullous pemphigoid vitiligo split skin grafting localized bullous pemphigoid stability in vitiligo |
| url | https://journals.lww.com/10.4103/pigmentinternational_4_23 |
| work_keys_str_mv | AT siddharthbhatt bullouspemphigoidaftersplitskingraftinginvitiligopatient AT anandmannu bullouspemphigoidaftersplitskingraftinginvitiligopatient AT gourangpaliwal bullouspemphigoidaftersplitskingraftinginvitiligopatient AT bijuvasudevan bullouspemphigoidaftersplitskingraftinginvitiligopatient |