Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risks

Triclosan (TCS), a widely used antimicrobial agent, has become an emerging environmental contaminant due to its extensive application in pharmaceutical and personal care products. Its persistence, high lipophilicity, and bioaccumulative nature contribute to its widespread presence in various environ...

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Main Authors: Dipti Agarwal, Komal Sharma, Hari Dev Chaudhary, Upma Bhatt, Vineet Soni
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Next Sustainability
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949823625000509
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author Dipti Agarwal
Komal Sharma
Hari Dev Chaudhary
Upma Bhatt
Vineet Soni
author_facet Dipti Agarwal
Komal Sharma
Hari Dev Chaudhary
Upma Bhatt
Vineet Soni
author_sort Dipti Agarwal
collection DOAJ
description Triclosan (TCS), a widely used antimicrobial agent, has become an emerging environmental contaminant due to its extensive application in pharmaceutical and personal care products. Its persistence, high lipophilicity, and bioaccumulative nature contribute to its widespread presence in various environmental compartments, particularly aquatic and terrestrial ecosystems. This review explores the eco-toxicological impacts of TCS on plant systems, emphasizing its sources, bioaccumulation, and adverse effects on plant physiology, including oxidative stress, impaired photosynthesis, and biochemical disruptions. The ability of TCS to accumulate in agricultural soils via wastewater irrigation and biosolid application raises significant concerns about food security and ecosystem stability. Additionally, the review discusses the transformation and degradation of TCS in plant systems, highlighting its metabolic pathways and interactions with plant-associated microbiomes. Given its documented endocrine-disrupting properties, phytotoxicity, potential role in antimicrobial resistance, and adverse cascading effects on food chains, biodiversity, and ecosystem, the review underscores the urgent need for improved wastewater treatment protocols and sustainable remediation strategies for TCS.
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spelling doaj-art-ce7db01f30794fac808726df64a7466f2025-08-20T03:15:08ZengElsevierNext Sustainability2949-82362025-01-01610014710.1016/j.nxsust.2025.100147Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risksDipti Agarwal0Komal Sharma1Hari Dev Chaudhary2Upma Bhatt3Vineet Soni4Plant bioenergetics and biochemistry laboratory, Mohanlal Sukhadia University Udaipur, Rajasthan, IndiaPlant bioenergetics and biochemistry laboratory, Mohanlal Sukhadia University Udaipur, Rajasthan, IndiaPlant bioenergetics and biochemistry laboratory, Mohanlal Sukhadia University Udaipur, Rajasthan, IndiaPlant bioenergetics and biochemistry laboratory, Mohanlal Sukhadia University Udaipur, Rajasthan, IndiaCorresponding author.; Plant bioenergetics and biochemistry laboratory, Mohanlal Sukhadia University Udaipur, Rajasthan, IndiaTriclosan (TCS), a widely used antimicrobial agent, has become an emerging environmental contaminant due to its extensive application in pharmaceutical and personal care products. Its persistence, high lipophilicity, and bioaccumulative nature contribute to its widespread presence in various environmental compartments, particularly aquatic and terrestrial ecosystems. This review explores the eco-toxicological impacts of TCS on plant systems, emphasizing its sources, bioaccumulation, and adverse effects on plant physiology, including oxidative stress, impaired photosynthesis, and biochemical disruptions. The ability of TCS to accumulate in agricultural soils via wastewater irrigation and biosolid application raises significant concerns about food security and ecosystem stability. Additionally, the review discusses the transformation and degradation of TCS in plant systems, highlighting its metabolic pathways and interactions with plant-associated microbiomes. Given its documented endocrine-disrupting properties, phytotoxicity, potential role in antimicrobial resistance, and adverse cascading effects on food chains, biodiversity, and ecosystem, the review underscores the urgent need for improved wastewater treatment protocols and sustainable remediation strategies for TCS.http://www.sciencedirect.com/science/article/pii/S2949823625000509Antimicrobial resistanceBioaccumulationEnvironmental contaminationTriclosanPhytotoxicityOxidative stress
spellingShingle Dipti Agarwal
Komal Sharma
Hari Dev Chaudhary
Upma Bhatt
Vineet Soni
Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risks
Next Sustainability
Antimicrobial resistance
Bioaccumulation
Environmental contamination
Triclosan
Phytotoxicity
Oxidative stress
title Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risks
title_full Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risks
title_fullStr Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risks
title_full_unstemmed Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risks
title_short Comprehensive insights into Triclosan: Environmental sources, plant uptake, metabolism, phytotoxicity, and food safety risks
title_sort comprehensive insights into triclosan environmental sources plant uptake metabolism phytotoxicity and food safety risks
topic Antimicrobial resistance
Bioaccumulation
Environmental contamination
Triclosan
Phytotoxicity
Oxidative stress
url http://www.sciencedirect.com/science/article/pii/S2949823625000509
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