Bayesian inference of a spatially dependent semi-Markovian model with application to Madagascar Covid'19 data.

This article presents an approach to stochastic analysis of disease dynamics. We develop an explicit semi-Markovian model that accounts for spatial dependence, operating in discrete time over a finite state space. The model allowed us to have a propagation model conditioned by neighboring states and...

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Bibliographic Details
Main Authors: Angelo Raherinirina, Stefana Tabera Tsilefa, Tsidikaina Nirilanto, Solym M Manou-Abi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326264
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Summary:This article presents an approach to stochastic analysis of disease dynamics. We develop an explicit semi-Markovian model that accounts for spatial dependence, operating in discrete time over a finite state space. The model allowed us to have a propagation model conditioned by neighboring states and quantifies two key characteristics : spatial propagation timescales and propagation law in a region dependent on neighboring states. The model is inferred from data collected on the spread of Covid'19 in Madagascar's 22 regions, using the Bayesian approach to get a better idea of model parameter values. The result has demonstrated the effect of neighborhoods on the propagation dynamics of diseases. We conclude with a discussion of potential future theoretical developments.
ISSN:1932-6203